Mullapudi Abhishek P, Luu Lydia A, Noland Mary
Department of Dermatology, University of Virginia, Charlottesville, USA.
Department of Dermatology, University of Minnesota, Minneapolis, USA.
Cureus. 2025 May 30;17(5):e85076. doi: 10.7759/cureus.85076. eCollection 2025 May.
Sarcoidosis is a systemic inflammatory disease affecting multiple organs including the skin, lungs, and kidneys. This case report describes a man in his late 20s presenting with recurrent kidney stones and a one-year history of progressive, asymptomatic lesions on his scalp, forehead, trunk, and feet, with dyspnea on exertion. Biopsy confirmed cutaneous sarcoidosis, and further evaluation revealed pulmonary and renal involvement. He was treated with hydroxychloroquine and prednisone, leading to improvement in skin lesions. This case highlights the importance of recognizing cutaneous manifestations as potential indicators of systemic sarcoidosis, and the need for a comprehensive, multidisciplinary approach to diagnosis and management.
结节病是一种影响多个器官(包括皮肤、肺和肾脏)的全身性炎症性疾病。本病例报告描述了一名28岁左右的男性,患有复发性肾结石,头皮、前额、躯干和足部有进行性、无症状病变且病史长达一年,伴有劳力性呼吸困难。活检证实为皮肤结节病,进一步评估显示肺部和肾脏受累。他接受了羟氯喹和泼尼松治疗,皮肤病变有所改善。本病例强调了认识皮肤表现作为全身性结节病潜在指标的重要性,以及采用全面、多学科方法进行诊断和管理的必要性。