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Modern Myeloma Therapy + Sustained Minimal Residual Disease-Negative = (Functional) Cure!

作者信息

Landgren Ola, Kazandjian Dickran

机构信息

Myeloma Program, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL.

出版信息

J Clin Oncol. 2022 Sep 1;40(25):2863-2866. doi: 10.1200/JCO.22.00622. Epub 2022 Jun 30.

DOI:10.1200/JCO.22.00622
PMID:35772041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9426854/
Abstract
摘要

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Minimal Residual Disease After Autologous Stem-Cell Transplant for Patients With Myeloma: Prognostic Significance and the Impact of Lenalidomide Maintenance and Molecular Risk.自体干细胞移植后多发性骨髓瘤患者的微小残留病：预后意义和来那度胺维持治疗及分子风险的影响。
J Clin Oncol. 2022 Sep 1;40(25):2889-2900. doi: 10.1200/JCO.21.02228. Epub 2022 Apr 4.
2
Early versus late response to daratumumab-based triplet therapies in patients with multiple myeloma: a pooled analysis of trials POLLUX, CASTOR and MAIA.基于达雷妥尤单抗的三联疗法治疗多发性骨髓瘤患者的早期与晚期应答：POLLUX、CASTOR 和 MAIA 试验的汇总分析。
Leuk Lymphoma. 2022 Jul;63(7):1669-1677. doi: 10.1080/10428194.2022.2038376. Epub 2022 Feb 10.
3
NCCN Guidelines® Insights: Multiple Myeloma, Version 3.2022.美国国立综合癌症网络（NCCN）指南见解：多发性骨髓瘤，2022年第3版
J Natl Compr Canc Netw. 2022 Jan;20(1):8-19. doi: 10.6004/jnccn.2022.0002.
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Prognostic value of minimal residual disease negativity in myeloma: combined analysis of POLLUX, CASTOR, ALCYONE, and MAIA.骨髓瘤中微小残留病阴性的预后价值：POLLUX、CASTOR、ALCYONE和MAIA的联合分析
Blood. 2022 Feb 10;139(6):835-844. doi: 10.1182/blood.2021011101.
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Dynamics of minimal residual disease in patients with multiple myeloma on continuous lenalidomide maintenance: a single-arm, single-centre, phase 2 trial.来那度胺持续维持治疗的多发性骨髓瘤患者微小残留病动态变化：一项单臂、单中心2期试验
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Nat Commun. 2020 Apr 21;11(1):1917. doi: 10.1038/s41467-020-15740-9.