Department of Applied Biology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria.
Department of Parasitology and Entomology, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria.
Korean J Parasitol. 2022 Jun;60(3):173-179. doi: 10.3347/kjp.2022.60.3.173. Epub 2022 Jun 30.
Malaria remains a global health threat. Approximately 97% of the population is at risk in sub-Saharan countries, particularly Nigeria. This study compared the performance of 2 diagnostic methods in assessing malaria endemicity in the rural communities of Ebonyi State, Nigeria. A total of 1,140 study participants were screened for malaria parasite using Rapid Diagnostic Test kits (RDT) in the field, while thick and thin films for microscopy were examined in the laboratory. Our result showed that malaria prevalence was 56.8 by RDT and 38.6% by microscopic test. Age group under 10 years had the highest prevalence of 28.9% (RDT) and 23.6% (microscopy), respectively. The highest prevalence of 19.5% by RDT was recorded in Onicha Local Government Area, while the highest prevalence of 13.4% with microscopy was recorded in Ezza North Local Government Area. The sensitivity and specificity of microscopic examination were both 100%, while those of RDT were 95.5% and 75.9%, respectively.
疟疾仍然是全球健康威胁。撒哈拉以南非洲国家，特别是尼日利亚，约有 97%的人口面临疟疾风险。本研究比较了两种诊断方法在评估尼日利亚埃邦伊州农村社区疟疾流行情况中的表现。共有 1140 名研究参与者在现场使用快速诊断检测试剂盒（RDT）进行疟疾寄生虫筛查，而在实验室中则检查了厚涂片和薄涂片进行显微镜检查。我们的结果显示，RDT 检测的疟疾患病率为 56.8%，显微镜检测的患病率为 38.6%。年龄在 10 岁以下的人群患病率最高，分别为 28.9%（RDT）和 23.6%（显微镜）。RDT 检测记录的最高患病率为 19.5%，出现在 Onicha 地方政府区，而显微镜检测记录的最高患病率为 13.4%，出现在 Ezza North 地方政府区。显微镜检查的敏感性和特异性均为 100%，而 RDT 的敏感性和特异性分别为 95.5%和 75.9%。
