Reiter A
Z Exp Chir Transplant Kunstliche Organe. 1987;20(1):55-60.
The substance Butyl-2-Cyanoacrylate (Firm Braun-Dexon) which is known by the trade name Histoacryl-blau was implanted in rats for the purpose of testing its cancer-producing properties. Of 44 animals evaluated eleven cases of sarcomas developed at the implantation site, that were apparently directly caused by the tissue binding substance. Therefore the use of this preparation in humans should be strongly restrained and employed under strict regulation especially in patients under the age of thirty.
以商品名Histoacryl-blau为人所知的丁基-2-氰基丙烯酸酯（布劳恩-德克松公司产品）被植入大鼠体内，以测试其致癌特性。在接受评估的44只动物中，有11例在植入部位发生了肉瘤，这些肉瘤显然是由组织黏合剂直接引起的。因此，应严格限制该制剂在人体中的使用，并在严格监管下使用，尤其是在30岁以下的患者中。
