Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781 039, Assam, India.
Med Biol Eng Comput. 2022 Sep;60(9):2501-2519. doi: 10.1007/s11517-022-02625-w. Epub 2022 Jun 30.
Lumbar spine fracture is typically treated by means of screw fixation, the primary aim of which is to reduce fracture by achieving bony union such that the spinal anatomy is restored. Pedicle screw fixation has certain advantages over conventional vertebral screws, e.g. 3-column fixation and improved surgical alignment. However, expandable pedicle screws have been reported to impart better anchorage as compared to conventional pedicle screws, both in case of healthy and osteoporotic bone. The clinical studies notwithstanding, there is a paucity of preclinical investigations on expandable pedicle screws used on lumbar vertebrae. By employing anatomically viable FE models, the present study intended to estimate stress-strain fields of a functional spinal unit (FSU) of intact L4-L5 vertebra and to further compare the same with FSUs instrumented with normal and expandable pedicle screws under different physiological loading condition. The various physiological loading regimes appeared to have significant influence on the overall load transfer in the L4-L5 vertebrae. The expandable pedicle screw predicted marginally improved anchorage as compared to the normal pedicle screws, with more contact area with the bone resulting in higher stresses (~ 1.6 MPa) and high strain at the contact sites. This is indicative of improved stability albeit having marginally greater risk of screw pullout. Greater area (15-80%) with peak stresses at the bone-screw interfaces also indicates lesser degree of stress shielding. Thus, stability aside, one may expect to have lower loosening issues too with the use of expandable pedicle screws.
腰椎骨折通常采用螺钉固定治疗,其主要目的是通过实现骨性愈合来减少骨折,从而恢复脊柱解剖结构。与传统的椎弓根螺钉相比,经皮椎弓根螺钉固定具有一定的优势,例如可实现三柱固定和改善手术对位。然而,与传统的椎弓根螺钉相比,可膨胀椎弓根螺钉在健康和骨质疏松骨中均具有更好的锚固作用。尽管有临床研究,但对于在腰椎上使用可膨胀椎弓根螺钉的临床前研究很少。本研究通过采用解剖学上可行的有限元模型,旨在评估完整的 L4-L5 椎体的功能单位(FSU)的应力-应变场,并进一步比较在不同生理负荷条件下,正常和可膨胀椎弓根螺钉固定的 FSU 的情况。各种生理负荷条件对 L4-L5 椎体的整体负荷传递有显著影响。与正常椎弓根螺钉相比,可膨胀椎弓根螺钉的锚固作用略有改善,与骨的接触面积更大,导致更高的(~1.6 MPa)应力和接触部位的高应变。这表明稳定性有所提高,尽管螺钉拔出的风险略高。骨-螺钉界面上的峰值应力的更大面积(15-80%)也表明了较小程度的应力屏蔽。因此,除了稳定性之外,使用可膨胀椎弓根螺钉还可能降低松动问题。