McCarty Todd P, Luethy Paul M, Baddley John W, Pappas Peter G
Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Department of Pathology, University of Maryland, Baltimore, MD, USA.
JAC Antimicrob Resist. 2022 Jun 28;4(3):dlac067. doi: 10.1093/jacamr/dlac067. eCollection 2022 Jun.
Invasive fungal diseases cause significant morbidity and mortality, in particular affecting immunocompromised patients. Resistant organisms are of increasing importance, yet there are many notable differences in the ability to both perform and interpret antifungal susceptibility testing compared with bacteria. In this review, we will highlight the strengths and limitations of resistance data of pathogenic yeasts and moulds that may be used to guide treatment and predict clinical outcomes.
侵袭性真菌病会导致严重的发病和死亡，尤其会影响免疫功能低下的患者。耐药菌的重要性日益增加，然而与细菌相比，在进行和解释抗真菌药敏试验的能力方面存在许多显著差异。在这篇综述中，我们将强调致病性酵母和霉菌耐药数据的优势和局限性，这些数据可用于指导治疗并预测临床结果。
