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本文引用的文献

1
Evaluation of Antifungal Drug Combinations against Multidrug-Resistant Candida auris Isolates from New York Outbreak.针对来自纽约疫情的多重耐药耳念珠菌分离株的抗真菌药物联合评估
Antimicrob Agents Chemother. 2020 Mar 24;64(4). doi: 10.1128/AAC.02195-19.
2
Candida auris Isolates Resistant to Three Classes of Antifungal Medications - New York, 2019.耳念珠菌对三类抗真菌药物耐药——纽约,2019 年。
MMWR Morb Mortal Wkly Rep. 2020 Jan 10;69(1):6-9. doi: 10.15585/mmwr.mm6901a2.
3
Laboratory Analysis of an Outbreak of Candida auris in New York from 2016 to 2018: Impact and Lessons Learned.2016年至2018年纽约耳念珠菌暴发的实验室分析:影响与经验教训
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Emerg Infect Dis. 2019 Sep;25(9):1780-1781. doi: 10.3201/eid2509.190686. Epub 2019 Sep 17.
5
Development of High-Level Echinocandin Resistance in a Patient With Recurrent Candidemia Secondary to Chronic Candiduria.慢性念珠菌尿继发复发性念珠菌血症患者中高水平棘白菌素耐药性的产生
Open Forum Infect Dis. 2019 Jun 1;6(7):ofz262. doi: 10.1093/ofid/ofz262. eCollection 2019 Jul.
6
Candida auris in Healthcare Facilities, New York, USA, 2013-2017.美国纽约,2013-2017 年医疗机构中的耳念珠菌。
Emerg Infect Dis. 2018 Oct;24(10):1816-1824. doi: 10.3201/eid2410.180649.
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Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses.全基因组测序和流行病学分析证实三大洲同时出现多重耐药性耳念珠菌
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Investigation of the First Seven Reported Cases of Candida auris, a Globally Emerging Invasive, Multidrug-Resistant Fungus - United States, May 2013-August 2016.调查美国 2013 年 5 月至 2016 年 8 月首例报告的 7 例耳念珠菌感染病例,这是一种全球新兴的侵袭性、多药耐药真菌。
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9
First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia.美国首次报告耳念珠菌感染:18 例念珠菌血症的临床和微生物学特征。
J Infect. 2016 Oct;73(4):369-74. doi: 10.1016/j.jinf.2016.07.008. Epub 2016 Jul 21.
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The role of epidemiological cutoff values (ECVs/ECOFFs) in antifungal susceptibility testing and interpretation for uncommon yeasts and moulds.流行病学截断值(ECV/ECOFF)在罕见酵母菌和霉菌抗真菌药敏试验及结果判读中的作用
Rev Iberoam Micol. 2016 Apr-Jun;33(2):63-75. doi: 10.1016/j.riam.2016.04.001. Epub 2016 Jun 11.

2016 年至 2020 年纽约和新泽西州耳念珠菌临床分离株的抗真菌耐药趋势。

Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020.

机构信息

New York State Department of Health, Albany, New York, USA.

New Jersey Department of Health, Trenton, New Jersey, USA.

出版信息

Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0224221. doi: 10.1128/aac.02242-21. Epub 2022 Jan 10.

DOI:10.1128/aac.02242-21
PMID:35007140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8923207/
Abstract

About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to <1% for New York C. auris clinical isolates but not for New Jersey, highlighting the regional differences.

摘要

从 2016 年到 2020 年,美国约有 55%的假丝酵母菌属耳念珠菌临床病例报告来自纽约和新泽西。几乎所有来自纽约-新泽西的临床分离株(99.8%)对氟康唑具有耐药性,50%对两性霉素 B 具有耐药性。棘白菌素类耐药性从 0%增加到 4%,泛耐药性从 0%增加到纽约耳念珠菌临床分离株的<1%,但新泽西没有增加,突出了区域差异。