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2016 年至 2020 年纽约和新泽西州耳念珠菌临床分离株的抗真菌耐药趋势。

Antifungal Resistance Trends of Candida auris Clinical Isolates in New York and New Jersey from 2016 to 2020.

机构信息

New York State Department of Health, Albany, New York, USA.

New Jersey Department of Health, Trenton, New Jersey, USA.

出版信息

Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0224221. doi: 10.1128/aac.02242-21. Epub 2022 Jan 10.

Abstract

About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to <1% for New York C. auris clinical isolates but not for New Jersey, highlighting the regional differences.

摘要

从 2016 年到 2020 年,美国约有 55%的假丝酵母菌属耳念珠菌临床病例报告来自纽约和新泽西。几乎所有来自纽约-新泽西的临床分离株(99.8%)对氟康唑具有耐药性,50%对两性霉素 B 具有耐药性。棘白菌素类耐药性从 0%增加到 4%,泛耐药性从 0%增加到纽约耳念珠菌临床分离株的<1%,但新泽西没有增加,突出了区域差异。

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