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[血管加压素类似物对完整大鼠及蓝斑损毁后临时连接固定的影响]

[Effect of an analog of vasopressin on the fixation of temporary connections in the intact rat and after destruction of the locus coeruleus].

作者信息

Kruglikov R I, Orlova N V, Mats V N, Sarychev E I, Iosht K

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Jan-Feb;37(1):95-9.

PMID:3577423
Abstract

Subcutaneous injection to intact rats and rats with destroyed locus coeruleus of 10 mcg of triglycide-glycinamide-lysinevasopressin (TGDGA-LVP) immediately after elaboration of labyrinth defensive conditioned reflex improves consolidation of temporary connections and raises its resistance to extinction. Improved consolidation of temporary connection is retained in animals with destroyed locus coeruleus for a shorter time than in intact animals. At the same time according to some characteristics, TGDGA-LVP has a more expressed influence of positive character on animals with destroyed locus coeruleus than on intact rats.

摘要

在建立迷宫防御性条件反射后，立即给完整大鼠和蓝斑损毁大鼠皮下注射10微克的甘油三肽 - 甘氨酰胺 - 赖氨酸加压素（TGDGA - LVP），可改善暂时联系的巩固，并提高其对消退的抵抗力。与完整动物相比，蓝斑损毁动物中暂时联系巩固的改善维持时间较短。同时，根据某些特征，TGDGA - LVP对蓝斑损毁动物的积极影响比对完整大鼠的影响更明显。

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Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Jan-Feb;37(1):95-9.
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