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中心型肥胖与老年人多部位疼痛发生率增加相关。

Central Obesity Is Associated With an Increased Rate of Multisite Pain in Older Adults.

机构信息

Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States.

出版信息

Front Public Health. 2022 Jun 14;10:735591. doi: 10.3389/fpubh.2022.735591. eCollection 2022.

Abstract

OBJECTIVE

Central obesity has been associated with several adverse health events, but little research exists about the longitudinal effects of central obesity on multisite pain. The purpose of this study was to assess if central obesity, as measured by waist circumference measurement, was associated with an increased rate of having multisite pain among older adults aged 65 years and older.

DESIGN

The National Health and Aging Trends Study is a longitudinal cohort study initiated in 2011 and intended to be representative of Medicare beneficiaries in the contiguous United States.

METHODS

There were 7,145 community-dwelling participants included in this study. Data for this study were collected annually between 2011 and 2018. Researchers assessed if waist circumference risk level was associated with an increased rate ratio of multisite pain. Weighted data were used in a multivariable generalized estimating equation model that used a log link specified with a Poisson distribution.

RESULTS

Participants with high-risk waist circumferences (98 cm or greater for women and 109 cm or greater for men) had a 11% higher rate of multisite pain than those with low-risk waist circumferences [rate ratio () 1.11, 95% : 1.07-1.15] adjusting for gender, age, race, education, probable major depression, arthritis, and multimorbidity count.

CONCLUSION

As measured by waist circumference, central adiposity is associated with multisite pain in older adults. While more research is needed, reducing waist circumference may prove beneficial in reducing the burden of multisite pain.

摘要

目的

中心性肥胖与多种不良健康事件有关,但关于中心性肥胖对多部位疼痛的纵向影响的研究甚少。本研究旨在评估腰围测量的中心性肥胖是否与 65 岁及以上老年人多部位疼痛的发生率增加有关。

设计

国家健康老龄化趋势研究是一项纵向队列研究,于 2011 年启动,旨在代表美国大陆的医疗保险受益人。

方法

本研究纳入了 7145 名居住在社区的参与者。本研究的数据收集于 2011 年至 2018 年之间每年进行一次。研究人员评估了腰围风险水平是否与多部位疼痛的发生率比值增加有关。使用多变量广义估计方程模型对加权数据进行分析,该模型使用指定泊松分布的对数链接。

结果

与低风险腰围(女性腰围≥98cm,男性腰围≥109cm)相比,高风险腰围(女性腰围≥98cm,男性腰围≥109cm)的参与者多部位疼痛的发生率高出 11%[率比(RR)1.11,95%置信区间(CI):1.07-1.15],调整性别、年龄、种族、教育程度、可能患有重度抑郁症、关节炎和多种合并症的数量后。

结论

以腰围衡量,中心性肥胖与老年人的多部位疼痛有关。虽然还需要更多的研究,但减少腰围可能有助于减轻多部位疼痛的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a23d/9239402/79106199eb48/fpubh-10-735591-g0001.jpg

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