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肥胖与下肢多部位疼痛:来自骨关节炎倡议的数据。

Obesity and Multisite Pain in the Lower Limbs: Data from the Osteoarthritis Initiative.

机构信息

Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Lawrence, Kansas, USA.

出版信息

Pain Res Manag. 2020 Jul 9;2020:6263505. doi: 10.1155/2020/6263505. eCollection 2020.

DOI:10.1155/2020/6263505
PMID:32695246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7368928/
Abstract

BACKGROUND

Although several studies investigated the relationship between obesity, osteoarthritis, and pain, no study examined the association between obesity and multijoint pain in the lower limbs. The purpose of this study was to address this gap.

METHOD

This cross-sectional study was performed in Riyadh, Saudi Arabia, between March and April 2019. In this study, a total of 4,661 adults aged 45-79 years with or at high risk for knee osteoarthritis were included from the Osteoarthritis Initiative. The persons who had an elevated risk of developing symptoms of knee osteoarthritis during the study were defined as high risk for knee osteoarthritis. According to the body mass index, participants were categorized into three groups: normal weight ( = 1,068), overweight ( = 1,832), and obese ( = 1,761). Logistic regression was used to examine the association between obesity and multisite pain.

RESULTS

The odds of multisite pain was associated significantly ( < 0.001) by 1.36 times higher with obesity than normal weight, no, or sigle-site pain, even after adjusting for sociodemographic and health variables.

CONCLUSION

Obesity is associated with an increased likelihood of multisite pain in the lower limbs. The results enable clinicians to adopt better standards of practice for the prevention and screening of multisite pain in this community.

摘要

背景

尽管有几项研究调查了肥胖、骨关节炎和疼痛之间的关系,但没有研究检查肥胖与下肢多关节疼痛之间的关联。本研究旨在解决这一差距。

方法

本横断面研究于 2019 年 3 月至 4 月在沙特阿拉伯利雅得进行。在这项研究中,从骨关节炎倡议中总共纳入了 4661 名年龄在 45-79 岁、有或有膝关节骨关节炎高风险的成年人。在研究期间有发展膝关节骨关节炎症状风险升高的人被定义为有膝关节骨关节炎高风险。根据体重指数,参与者分为三组:正常体重( = 1068)、超重( = 1832)和肥胖( = 1761)。使用逻辑回归来检查肥胖与多部位疼痛之间的关联。

结果

肥胖与多部位疼痛显著相关(<0.001),肥胖患者发生多部位疼痛的几率比正常体重、无疼痛或单部位疼痛患者高 1.36 倍,即使在调整了社会人口统计学和健康变量后也是如此。

结论

肥胖与下肢多部位疼痛的可能性增加有关。研究结果使临床医生能够在这个社区采用更好的多部位疼痛预防和筛查标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a55/7368928/e0f7d44e9783/PRM2020-6263505.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a55/7368928/bccdbc321854/PRM2020-6263505.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a55/7368928/e0f7d44e9783/PRM2020-6263505.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a55/7368928/bccdbc321854/PRM2020-6263505.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a55/7368928/e0f7d44e9783/PRM2020-6263505.002.jpg

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2
A retrospective study on association between obesity and cardiovascular risk diseases with aging in Chinese adults.一项针对中国成年人肥胖与心血管疾病风险随年龄增长的相关性的回顾性研究。
Sci Rep. 2018 Apr 11;8(1):5806. doi: 10.1038/s41598-018-24161-0.
3
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PLoS One. 2024 May 24;19(5):e0302051. doi: 10.1371/journal.pone.0302051. eCollection 2024.
4
Associations Among Knee Osteoarthritis Severity, Body Mass Index, and Physical Functions in Saudi Arabian Adults: A Multi-Center Cross-Sectional Study.沙特阿拉伯成年人膝关节骨关节炎严重程度、体重指数与身体功能之间的关联:一项多中心横断面研究。
Cureus. 2023 Nov 1;15(11):e48130. doi: 10.7759/cureus.48130. eCollection 2023 Nov.
5
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6
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7
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