Editorial: Intranasal Delivery of Central Nervous System Active Drugs: Opportunities and Challenges.
作者信息
Rodrigues Márcio, Ali Javed, Alves Gilberto
机构信息
CICS-UBI-Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal.
CPIRN-UDI-IPG-Center for Potential and Innovation of Natural Resources, Research Unit for Inland Development, Polytechnic Institute of Guarda, Guarda, Portugal.
出版信息
Front Pharmacol. 2022 Jun 14;13:927812. doi: 10.3389/fphar.2022.927812. eCollection 2022.
Abstract
摘要
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本文引用的文献
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Pharmaceutics. 2022 Mar 8;14(3):588. doi: 10.3390/pharmaceutics14030588.
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Pharmacokinetics and safety of VALTOCO (NRL-1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri-ictal) and nonseizure (interictal) conditions: A phase 1, open-label study.VALTOCO（NRL-1；地西泮鼻喷雾剂）在癫痫患者发作（发作/发作间期）和非发作（发作间期）期间的药代动力学和安全性：一项 1 期、开放标签研究。
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Evaluation of intranasal delivery route of drug administration for brain targeting.评价经鼻给药途径用于脑部给药的效果。
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Rescue therapies for seizure emergencies: New modes of administration.癫痫紧急情况下的抢救治疗：新的给药方式。
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