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蛋白S缺乏症患者的循环中血栓

Clot In Transit in a Patient with Protein S Deficiency.

作者信息

Kashfi Simon, Nasser Mohamed Farhan, Soleiman Aron, Sharma Sapna, Koripalli Venkata Sandeep, Sharma Shorabh

机构信息

CUNY School of Medicine, New York, NY, USA.

Heart and Vascular Center, MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH, USA.

出版信息

Eur J Case Rep Intern Med. 2022 May 5;9(5):003355. doi: 10.12890/2022_003355. eCollection 2022.

DOI:10.12890/2022_003355
PMID:35774736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9239027/
Abstract

UNLABELLED

Clot in transit (CIT) is a rare condition in which a venous thromboembolism becomes lodged in the right heart. It is seen in up to 18% of patients with massive pulmonary embolism, and if left untreated, mortality rates are between 80% and 100%. The identification and management of CIT are crucial. However, there are no current guidelines for the treatment of CIT. We present the case of a 44-year-old woman who was found to have CIT that was ultimately treated with medical management.

LEARNING POINTS

Clot in transit (CIT) is a dangerous entity that must be promptly managed.Risk factors for CIT include a history of heart failure, a pre-existing central venous catheter and recent hospitalization.New interventions are emerging for the treatment of CIT.

摘要

未标注

移行性血栓(CIT)是一种罕见的病症,即静脉血栓栓塞栓子滞留于右心。在高达18%的大面积肺栓塞患者中可见,若不治疗,死亡率在80%至100%之间。CIT的识别与处理至关重要。然而,目前尚无治疗CIT的指南。我们报告一例44岁女性患者,其被诊断为CIT,最终接受了药物治疗。

学习要点

移行性血栓(CIT)是一种必须迅速处理的危险病症。CIT的危险因素包括心力衰竭病史、既往存在中心静脉导管以及近期住院。针对CIT的治疗正在出现新的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/d0d96e1f41e3/3355_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/a1e9fa23723f/3355_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/021f671fe0ef/3355_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/f78bf5f27e72/3355_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/d0d96e1f41e3/3355_Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/a1e9fa23723f/3355_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/021f671fe0ef/3355_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/f78bf5f27e72/3355_Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/873c/9239027/d0d96e1f41e3/3355_Fig4.jpg

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本文引用的文献

1
Procedural outcomes associated with use of the AngioVac System for right heart thrombi: A safety report from RAPID registry data.使用AngioVac系统治疗右心血栓的手术结果:来自RAPID注册数据的安全性报告。
Vasc Med. 2022 Jun;27(3):277-282. doi: 10.1177/1358863X211073974. Epub 2022 Feb 17.
2
Clot in Transit and Pulmonary Artery Percutaneous Mechanical Thrombectomy.行肺动脉经皮机械血栓切除术治疗移行性血栓
Kans J Med. 2021 Nov 5;14(3):287-289. doi: 10.17161/kjm.vol14.15601. eCollection 2021.
3
Commentary: Clot in transit: Catch it when you can.
评论:移动性血栓:抓住时机发现它。
JTCVS Tech. 2020 Sep 14;4:145-146. doi: 10.1016/j.xjtc.2020.08.073. eCollection 2020 Dec.
4
Catheter directed embolectomy of right atrial clot in transit-A case series.经导管右心房栓子清除术治疗转移中的右心房血栓:病例系列。
Catheter Cardiovasc Interv. 2021 Apr 1;97(5):869-873. doi: 10.1002/ccd.29391. Epub 2020 Nov 23.
5
Thrombus in Transit: Extract or Dissolve?行进中的血栓:取出还是溶解?
Cureus. 2020 Aug 4;12(8):e9550. doi: 10.7759/cureus.9550.
6
Clot in transit: a case of acute pulmonary embolism.移行性血栓:一例急性肺栓塞病例
BMJ Case Rep. 2020 Aug 17;13(8):e236494. doi: 10.1136/bcr-2020-236494.
7
Special Considerations in Pulmonary Embolism: Clot-in-Transit and Incidental Pulmonary Embolism.肺栓塞的特殊考虑:游走性血栓和偶发性肺栓塞。
Crit Care Clin. 2020 Jul;36(3):531-546. doi: 10.1016/j.ccc.2020.02.008. Epub 2020 May 7.
8
Pulmonary embolism with clot in transit: An analysis of risk factors and outcomes.肺栓塞伴栓子在运行中:危险因素与结局分析。
Thromb Res. 2020 Mar;187:139-147. doi: 10.1016/j.thromres.2020.01.006. Epub 2020 Jan 10.
9
2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS).2019年欧洲心脏病学会(ESC)与欧洲呼吸学会(ERS)合作制定的急性肺栓塞诊断和管理指南。
Eur Heart J. 2020 Jan 21;41(4):543-603. doi: 10.1093/eurheartj/ehz405.
10
Epidemiology, Pathophysiology, and Natural History of Pulmonary Embolism.肺栓塞的流行病学、病理生理学及自然史
Semin Intervent Radiol. 2018 Jun;35(2):92-98. doi: 10.1055/s-0038-1642036. Epub 2018 Jun 4.