脊柱内固定手术后手术部位感染的管理:取出植入物与保留植入物:一项更新的系统评价

Surgical Site Infection Management following Spinal Instrumentation Surgery: Implant Removal vs. Implant Retention: an Updated Systematical Review.

作者信息

Yudistira Andhika, Asmiragani Syaifullah, Imran Abdul Waris, Sugiarto Muhammad Alwy

机构信息

Orthopaedic and Traumatology Department, Faculty of Medicine, University of Brawijaya, Saiful Anwar General Hospital, Malang, East Java, Indonesia.

出版信息

Acta Inform Med. 2022 Jun;30(2):115-120. doi: 10.5455/aim.2022.30.115-120.

Abstract

BACKGROUND

The number of lumbar spine surgery increased in recent years. Spinal instrumentation surgery was an integral component in the treatment of spinal pathologies, which can cause surgical site infection (SSI). Surgical site infections (SSIs) are the leading cause of mortality and morbidity after spinal instrumentation surgery. The management of SSI was implant retention and removal is still unclear.

OBJECTIVE

The objective of this literature is to systematically review the implant removal and retention method for SSI management after spinal instrumentation surgery.

METHODS

We searched in PubMed and ScienceDirect for cohort and randomized control trial studies in English, published between 2002 and 2022, which had data on patients with spinal instrumentation surgery. The underlying disease, comorbidities, common bacteria, type of infection, the onset of infection, implant removal, and retention percentage and recommendation were analyzed. Bias analysis using Newcastle-Ottawa Quality Assessment.

RESULTS

We included 15 studies with a total sample were 2.584 with an average of age 15 to 66 years old. The most common organism detected were S. Aureus, MRSA, and S. Epidermis. The most common surgical procedure indications were degenerative followed by scoliosis. Implant removal and retention rate were 0-100% and 0-90,32% respectively. Implant removal is more frequently used in patients after spinal instrumentation surgery than the implant retention method.

CONCLUSION

Implant retention can be performed in case of SSI is < 3 months after surgery. Implant removal is recommended if the incidence of SSI is > 3 months. Empirical antibiotics therapy is necessary to reduce the possibility of implant removal after debridement. Further studies on the effect of implant removal and retention in patients on infection recurrence, pain, and quality of life of patients are needed.

摘要

背景

近年来腰椎手术数量有所增加。脊柱内固定手术是治疗脊柱疾病的重要组成部分,但可能导致手术部位感染(SSI)。手术部位感染是脊柱内固定手术后死亡和发病的主要原因。对于SSI的处理,植入物的保留和取出仍不明确。

目的

本文献的目的是系统回顾脊柱内固定手术后SSI处理中植入物取出和保留的方法。

方法

我们在PubMed和ScienceDirect中检索了2002年至2022年期间发表的英文队列研究和随机对照试验研究,这些研究包含脊柱内固定手术患者的数据。分析了基础疾病、合并症、常见细菌、感染类型、感染发作、植入物取出、保留百分比及建议。使用纽卡斯尔-渥太华质量评估进行偏倚分析。

结果

我们纳入了15项研究,总样本量为2584例,平均年龄为15至66岁。检测到的最常见病原体为金黄色葡萄球菌、耐甲氧西林金黄色葡萄球菌和表皮葡萄球菌。最常见的手术适应证是退行性病变,其次是脊柱侧弯。植入物取出率和保留率分别为0 - 100%和0 - 90.32%。脊柱内固定手术后患者中,植入物取出的使用频率高于植入物保留方法。

结论

如果术后SSI发生时间<3个月,可进行植入物保留。如果SSI发生时间>3个月,建议取出植入物。经验性抗生素治疗对于减少清创后植入物取出的可能性是必要的。需要进一步研究植入物取出和保留对患者感染复发、疼痛及生活质量的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a791/9233457/245ee1744139/AIM-30-115-g001.jpg

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