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[酗酒患者及有或无酗酒家族史的健康受试者体内的内源性血液乙醇]

[Endogenous blood ethanol in alcoholic patients and healthy subjects with and without a family history of alcoholism].

作者信息

Pron'ko P S, Shishkin S N, Kolesnikov V B, Volynets S I, Ostrovskiĭ Iu M

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(3):417-22.

PMID:3577537
Abstract

Levels of endogenous ethanol were studied in healthy males, 12-13-year-old boys (sons of alcoholics and normal fathers) and alcoholic patients (after discontinuation of all drugs). The results showed no significant differences between the groups. On the other hand endogenous ethanol concentrations were higher than normal in oligophrenic boys irrespective of whether their fathers were alcoholics or healthy subjects. In the abstinence period endogenic ethanol concentrations were the minimal in patients with delirium tremens and a severe abstinence syndrome, the dynamics of this parameter in the process of treatment being dependent on the severity of the abstinence syndrome and on the nature of treatment.

摘要

对健康男性、12 - 13岁男孩(酗酒者之子和正常父亲的儿子)以及酒精性患者(停用所有药物后)的内源性乙醇水平进行了研究。结果显示,各组之间无显著差异。另一方面,无论父亲是酗酒者还是健康受试者,智力发育迟缓男孩的内源性乙醇浓度均高于正常水平。在戒酒期,震颤谵妄和严重戒酒综合征患者的内源性乙醇浓度最低,该参数在治疗过程中的动态变化取决于戒酒综合征的严重程度和治疗性质。

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