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1

Migraine relief in 20 minutes using eyedrops?20 分钟内用眼药水缓解偏头痛？

J Fam Pract. 2022 Jun;71(5):222-224. doi: 10.12788/jfp.0427.

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Short-term Efficacy and Safety of Topical β-Blockers (Timolol Maleate Ophthalmic Solution, 0.5%) in Acute Migraine: A Randomized Crossover Trial.局部β-阻滞剂（马来酸噻吗洛尔滴眼液，0.5%）治疗急性偏头痛的短期疗效和安全性：一项随机交叉试验。

JAMA Ophthalmol. 2020 Nov 1;138(11):1160-1166. doi: 10.1001/jamaophthalmol.2020.3676.

3

Timolol Eyedrops in the Treatment of Acute Migraine Attacks: A Randomized Crossover Study.噻吗洛尔滴眼液治疗急性偏头痛发作的随机交叉研究。

JAMA Neurol. 2018 Aug 1;75(8):1024-1025. doi: 10.1001/jamaneurol.2018.0970.

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Time to pain freedom and onset of pain relief with rizatriptan 10 mg and prescription usual-care oral medications in the acute treatment of migraine headaches: a multicenter, prospective, open-label, two-attack, crossover study.10毫克利扎曲普坦与处方常用口服药物治疗偏头痛急性发作时达到无痛状态的时间及疼痛缓解起效时间：一项多中心、前瞻性、开放标签、两发作期、交叉研究。

Clin Ther. 2006 Jun;28(6):872-80. doi: 10.1016/j.clinthera.2006.06.006.

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AVP-825 breath-powered intranasal delivery system containing 22 mg sumatriptan powder vs 100 mg oral sumatriptan in the acute treatment of migraines (The COMPASS study): a comparative randomized clinical trial across multiple attacks.含22毫克舒马曲坦粉末的AVP - 825呼吸驱动鼻内给药系统与100毫克口服舒马曲坦用于偏头痛急性治疗的比较（COMPASS研究）：一项针对多次发作的比较随机临床试验

Headache. 2015 May;55(5):621-35. doi: 10.1111/head.12583. Epub 2015 May 4.

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Early Onset of Efficacy and Consistency of Response Across Multiple Migraine Attacks From the Randomized COMPASS Study: AVP-825 Breath Powered Exhalation Delivery System (Sumatriptan Nasal Powder) vs Oral Sumatriptan.随机COMPASS研究中AVP - 825呼吸驱动呼气给药系统（舒马曲坦鼻粉）与口服舒马曲坦在多次偏头痛发作中的早期疗效及反应一致性

Headache. 2017 Jun;57(6):862-876. doi: 10.1111/head.13105. Epub 2017 May 11.

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Two replicate randomized, double-blind, placebo-controlled trials of the time to onset of pain relief in the acute treatment of migraine with a fast-disintegrating/rapid-release formulation of sumatriptan tablets.两项关于使用舒马曲坦片速崩/速释制剂急性治疗偏头痛时疼痛缓解起效时间的重复随机、双盲、安慰剂对照试验。

Clin Ther. 2005 Apr;27(4):407-17. doi: 10.1016/j.clinthera.2005.04.003.

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Faster Improvement in Migraine Pain Intensity and Migraine-Related Disability at Early Time Points with AVP-825 (Sumatriptan Nasal Powder Delivery System) versus Oral Sumatriptan: A Comparative Randomized Clinical Trial Across Multiple Attacks from the COMPASS Study.与口服舒马曲坦相比，AVP-825（舒马曲坦鼻内粉雾剂输送系统）在早期时间点更快地改善偏头痛疼痛强度和偏头痛相关残疾：来自 COMPASS 研究的多次发作比较随机临床试验。

Headache. 2017 Nov;57(10):1570-1582. doi: 10.1111/head.13165. Epub 2017 Sep 7.

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A Randomized Trial of Ketorolac vs. Sumatripan vs. Placebo Nasal Spray (KSPN) for Acute Migraine.酮咯酸、舒马曲坦与安慰剂鼻喷雾剂（KSPN）治疗急性偏头痛的随机试验

Headache. 2016 Feb;56(2):331-40. doi: 10.1111/head.12767. Epub 2016 Feb 3.

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Beta blocker eye drops for treatment of acute migraine.用于治疗急性偏头痛的β受体阻滞剂眼药水。

Mo Med. 2014 Jul-Aug;111(4):283-8.

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20 分钟内用眼药水缓解偏头痛？

Migraine relief in 20 minutes using eyedrops?

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