Faculty of Bioresources and Environmental Sciences, Ishikawa Prefectural University, Nonoichi, Ishikawa, Japan.
Chemistry/Food Department, Industrial Research Institute of Ishikawa, Kanazawa, Ishikawa, Japan.
Biosci Biotechnol Biochem. 2022 Aug 24;86(9):1207-1210. doi: 10.1093/bbb/zbac106.
The structure and inhibitory activity of advanced glycation end products (AGEs) formation were studied using six model compounds and seven phlorotannins isolated from brown alga Ecklonia stolonifera. As a result, it was inferred that AGEs formation inhibitory activity was stronger when electron-rich groups were present because of the addition of many oxygen atoms to the phlorotannins.
采用 6 种模型化合物和 7 种采自褐藻鹿角菜的岩藻多酚对糖基化终产物（AGEs）的结构及其抑制活性进行了研究。结果表明，由于岩藻多酚中增加了许多氧原子，使得具有富电子基团的岩藻多酚具有更强的 AGEs 形成抑制活性。
