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人参补充剂对疾病相关疲劳的疗效:系统评价和荟萃分析。

Efficacy of ginseng supplements on disease-related fatigue: A systematic review and meta-analysis.

机构信息

Changchun University of Chinese Medicine, Jingyue Economic Development District, Changchun, People's Republic of China.

出版信息

Medicine (Baltimore). 2022 Jul 1;101(26):e29767. doi: 10.1097/MD.0000000000029767.

DOI:10.1097/MD.0000000000029767
PMID:35776997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9239648/
Abstract

BACKGROUND

Ginseng has been believed to provide energy, physical health, and well-being to patients for hundreds of years. Fatigue is a multidimensional symptom with unknown etiology and varying severity, and lots of patients suffer from fatigue.

METHODS

We search for research of ginseng treatment of disease-related fatigue in adult patients in Pubmed, Embase, Medline, and Cochrane library. Two independent reviewers assessed included studies and met to develop consensus on included studies. And we used Review Manager 5.3 software to evaluate the risk of bias.

RESULTS

The present meta-analysis included 12 randomized controlled trial containing 1298 patients. In the fixed-effect meta-analysis of 12 randomized controlled trial, ginseng supplements had a statistically significant efficacy on disease-related fatigue reduction (standardized mean difference = 0.33, 95% confidence interval = 0.44-0.22).

CONCLUSIONS

The use of ginseng supplements is benefit for patients to reduce disease-related fatigue.

摘要

背景

数百年来,人参一直被认为能为患者提供能量、身体健康和幸福感。疲劳是一种多维症状,病因不明,严重程度不一,很多患者都深受其困扰。

方法

我们在 Pubmed、Embase、Medline 和 Cochrane 图书馆中搜索了人参治疗成人患者疾病相关疲劳的研究。两位独立的审查员评估了纳入的研究,并开会就纳入的研究达成共识。我们使用 Review Manager 5.3 软件评估偏倚风险。

结果

本荟萃分析包括 12 项随机对照试验,共纳入 1298 名患者。在 12 项随机对照试验的固定效应荟萃分析中,人参补充剂在降低疾病相关疲劳方面具有统计学意义的疗效(标准化均数差=0.33,95%置信区间=0.44-0.22)。

结论

使用人参补充剂有益于患者减轻疾病相关疲劳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/d7ed152e8951/medi-101-e29767-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/b5b6816c16eb/medi-101-e29767-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/743442c07825/medi-101-e29767-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/ca090a10e355/medi-101-e29767-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/3f5f6a8cffd4/medi-101-e29767-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/d7ed152e8951/medi-101-e29767-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/b5b6816c16eb/medi-101-e29767-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/743442c07825/medi-101-e29767-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/ca090a10e355/medi-101-e29767-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/3f5f6a8cffd4/medi-101-e29767-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd1/9239648/d7ed152e8951/medi-101-e29767-g005.jpg

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