Green Catalysis Center, College of Chemistry, Zhengzhou University, Zhengzhou, China.
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, China.
Life Sci. 2022 Sep 15;305:120733. doi: 10.1016/j.lfs.2022.120733. Epub 2022 Jun 28.
Cardiovascular diseases (CVDs) are a leading cause of morbidity and mortality around the world. The physiological or pathological processes of CVDs can be well indicated by timely and accurate diagnosis of relevant biomarkers and function parameters. Nanosensors integrating the advantages of nanomaterials and sensing platforms have shown good potential for rapid diagnosis of CVDs, especially for early prediction. In this review, recent advances in nanosensors for the detection of CVDs are summarized, including electrochemical, optical, pressure, and paper-based nanosensors. Design strategies for different nanosensors and the corresponding sensing nanomaterials, mechanisms, and properties are briefly discussed. This review also offered a preliminary analysis of the obstacles and prospects for using nanosensors to diagnose CVDs.
心血管疾病(CVDs)是全球发病率和死亡率的主要原因。通过及时、准确地诊断相关生物标志物和功能参数,可以很好地指示 CVDs 的生理或病理过程。集纳材料和传感平台优势于一体的纳米传感器在 CVDs 的快速诊断方面表现出良好的应用潜力,尤其是在早期预测方面。本综述总结了用于 CVDs 检测的纳米传感器的最新进展,包括电化学、光学、压力和基于纸张的纳米传感器。简要讨论了不同纳米传感器的设计策略以及相应的传感纳米材料、机制和特性。本文还对利用纳米传感器诊断 CVDs 所面临的障碍和前景进行了初步分析。