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埃塞俄比亚感染艾滋病毒女性与双重避孕措施的使用:系统评价与荟萃分析

Women living with HIV and dual contraceptive use in Ethiopia: systematic review and meta-analysis.

作者信息

Ayenew Asteray

机构信息

Midwifery Department, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

出版信息

Contracept Reprod Med. 2022 Jul 2;7(1):11. doi: 10.1186/s40834-022-00179-8.

Abstract

BACKGROUND

Despite different preventive strategies that have been implemented in the country, the prevalence of HIV/AIDS is still significantly increasing in Ethiopia. The concurrence of HIV and unintended pregnancy makes the use of dual contraception a back bone for the simultaneous protection against HIV, and unintended pregnancy. As a result, this systematic review and meta-analysis aimed to assess the prevalence and associated factors of dual contraceptive use among women living with HIV in Ethiopia.

METHOD

We used databases; (PubMed, Google Scholar, EMBASE, Cochrane Library, African Online Journals, and Hinary), other gray and online repository accessed studies were searched using different search engines. For critical appraisal of studies Newcastle-Ottawa Quality Assessment Scale (NOS) was used. The analysis was done using STATA 11 software. The Cochran Q test and I test statistics were used to assess the heterogeneity. To detect publication bias funnel plot and Egger's test were used. The pooled prevalence of dual contraception use and the odds ratio (OR) with a 95% confidence interval was presented by using forest plots.

RESULT

Eleven studies were included in this review, with a total of 4083 women living with HIV in Ethiopia. The pooled prevalence of dual contraception use in Ethiopia was 34.08% (95%CI: 20.77-47.38). Having open partner discussion (OR = 3.96, 95%CI:2.3,6.8), provision of post test counseling (AOR = 4.38, 95%CI:2.93,6.54), disclosed HIV status to sexual partners (OR = 5.9, 95%CI:4.19,8.33), partner involvement in post-test counseling (OR = 3.52, 95%CI:2.37,5.23), and being on highly active antiretroviral therapy (HAART) (OR = 2.9, 95%CI:1.56,5.46) were the determinant factors of dual contraceptive use in Ethiopia.

CONCLUSION

The overall prevalence of dual contraceptive use among women living with HIV in Ethiopia was low. Having open partner discussion, provision of post-test counseling, disclosed HIV status to sexual partner, partner involvement in post-test counseling, and currently on highly active antiretroviral therapy (HAART) were the associated factors of dual contraceptive use. Therefore, efforts should be made to provide post-test counseling, and initiate partner involvement in post-test counseling. Moreover, promoting open partner discussion, counseling to disclose HIV status to their sexual partner and to start HAART will be helpful in enhancing the use of dual contraceptive method use.

摘要

背景

尽管该国已实施了不同的预防策略,但埃塞俄比亚的艾滋病毒/艾滋病患病率仍在显著上升。艾滋病毒与意外怀孕并存使得使用双重避孕措施成为同时预防艾滋病毒和意外怀孕的关键。因此,本系统评价和荟萃分析旨在评估埃塞俄比亚艾滋病毒感染者中双重避孕措施的使用患病率及相关因素。

方法

我们使用了数据库(PubMed、谷歌学术、EMBASE、考克兰图书馆、非洲在线期刊和Hinary),并使用不同的搜索引擎搜索了其他灰色文献和在线资源库中的研究。使用纽卡斯尔-渥太华质量评估量表(NOS)对研究进行批判性评价。分析使用STATA 11软件进行。采用Cochran Q检验和I检验统计量评估异质性。使用漏斗图和Egger检验检测发表偏倚。通过森林图呈现双重避孕措施使用的合并患病率及95%置信区间的比值比(OR)。

结果

本评价纳入了11项研究,共涉及埃塞俄比亚4083名艾滋病毒感染者。埃塞俄比亚双重避孕措施使用的合并患病率为34.08%(95%CI:20.77 - 47.38)。与伴侣进行开放式讨论(OR = 3.96,95%CI:2.3,6.8)、提供检测后咨询(校正OR = 4.38,95%CI:2.93,6.54)、向性伴侣披露艾滋病毒感染状况(OR = 5.9,95%CI:4.19,8.33)、伴侣参与检测后咨询(OR = 3.52,95%CI:2.37,5.23)以及接受高效抗逆转录病毒治疗(HAART)(OR = 2.9,95%CI:1.56,5.46)是埃塞俄比亚双重避孕措施使用的决定因素。

结论

埃塞俄比亚艾滋病毒感染者中双重避孕措施的总体使用率较低。与伴侣进行开放式讨论、提供检测后咨询、向性伴侣披露艾滋病毒感染状况、伴侣参与检测后咨询以及目前接受高效抗逆转录病毒治疗(HAART)是双重避孕措施使用的相关因素。因此,应努力提供检测后咨询,并促使伴侣参与检测后咨询。此外,促进与伴侣进行开放式讨论、咨询向性伴侣披露艾滋病毒感染状况以及开始接受HAART将有助于提高双重避孕方法的使用率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41ed/9250199/0d2e34a741c0/40834_2022_179_Fig1_HTML.jpg

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