Lygrisse Katherine A, Teo Greg, Singh Vivek, Muthusamy Nishanth, Schwarzkopf Ran, William Long
Department of Orthopedic Surgery, Huntington Hospital, Zucker School of Medicine Hofstra/Northwell, 270 Park Ave, Huntington, NY, 11743, USA.
Department of Orthopedic Surgery, Hospital for Special Surgeries, 541 East 71st St, 7th Fl, New York, NY, 10021, USA.
Arch Orthop Trauma Surg. 2023 Jun;143(6):2989-2995. doi: 10.1007/s00402-022-04530-1. Epub 2022 Jul 2.
High body mass index (BMI) and wound drainage following total joint arthroplasty (TJA) can lead to wound healing complications and periprosthetic joint infection. Silver-embedded occlusive dressings and negative pressure wound therapy (NPWT) have been shown to reduce these complications. The purpose of this prospective trial was to compare the effect of silver-embedded dressings and NPWT on wound complications in patients with BMI ≥ 35 m/kg2 undergoing TJA.
We conducted a randomized control trial of patients who had a BMI > 35 m/kg and were undergoing primary TJA between October 2017 and February 2020. Patients who underwent revision surgery, or those with an active infection, previous scar, history of wound healing complications, post-traumatic degenerative joint disease with hardware, or inflammatory arthritis were excluded. Patients were randomized to receive either a silver-embedded occlusive dressing (control) or NPWT. Frequency distributions, means, and standard deviations were used to describe patient demographics, postoperative complications, 90-day readmissions, and reoperations. T-test and chi-squared tests were used to test for significant differences between continuous and categorical variables, respectively.
Two hundred-thirty patients with 3-month follow-up were included. One-hundred-fifteen patients received the control and 115 patients received NPWT. There were six patients (5.2%) in the control group with wound complications (drainage: n = 5, non-healing wound: n = 1) and two patients (1.7%) in the NPWT with complications (drainage: n = 2). There were no 90-day readmissions in the control group versus two (1.8%) 90-day readmissions in the NPWT group. Finally, three patients (2.6%) in the control group underwent reoperations (irrigation and debridement [I&D], I&D with modular implant exchange, and implant revision), while none in the NPWT group had undergone reoperation. The two groups showed insignificant differences in wound complications (p = 0.28), 90-day readmissions (p = 0.50), and reoperations (p = 0.25).
Patients with BMI ≥ 35 m/kg2 undergoing TJA have no statistical difference in early wound complications, readmissions, or reoperations when treated with either silver-embedded dressings or NPWT.
高体重指数(BMI)以及全关节置换术(TJA)后的伤口引流可导致伤口愈合并发症和假体周围关节感染。含银封闭敷料和负压伤口治疗(NPWT)已被证明可减少这些并发症。这项前瞻性试验的目的是比较含银敷料和NPWT对BMI≥35m/kg²的TJA患者伤口并发症的影响。
我们对2017年10月至2020年2月期间BMI>35m/kg且正在接受初次TJA的患者进行了一项随机对照试验。排除接受翻修手术的患者,或有活动性感染、既往瘢痕、伤口愈合并发症史、伴有内固定的创伤后退行性关节病或炎性关节炎的患者。患者被随机分配接受含银封闭敷料(对照组)或NPWT。使用频率分布、均值和标准差来描述患者人口统计学、术后并发症、90天再入院情况和再次手术情况。分别使用t检验和卡方检验来检验连续变量和分类变量之间的显著差异。
纳入了230例有3个月随访的患者。115例患者接受了对照组治疗,115例患者接受了NPWT治疗。对照组有6例患者(5.2%)出现伤口并发症(引流:n = 5,伤口不愈合:n = 1),NPWT组有2例患者(1.7%)出现并发症(引流:n = 2)。对照组无90天再入院情况,而NPWT组有2例(1.8%)90天再入院。最后,对照组有3例患者(2.6%)接受了再次手术(冲洗清创术[I&D]、I&D联合模块化植入物置换以及植入物翻修),而NPWT组无患者接受再次手术。两组在伤口并发症(p = 0.28)、90天再入院情况(p = 0.50)和再次手术情况(p = 0.25)方面无显著差异。
BMI≥35m/kg²的TJA患者在接受含银敷料或NPWT治疗时,早期伤口并发症、再入院情况或再次手术情况无统计学差异。