Holzgreve W, Beller F K
Aesthetic Plast Surg. 1987;11(1):45-8. doi: 10.1007/BF01575482.
One hundred sixty three prophylactic subcutaneous mastectomies were performed during a six-year period in high-risk situations. All cases were evaluated for immediate surgical complications and followed up for at least five years. The postoperative complications following subcutaneous mastectomy with and without simultaneous reduction of skin were hematoma, infection, necrosis of the nipple area, pain, and impaired sensitivity. The most significant long-term complication was moderate to severe capsule formation. Despite these problems most women were satisfied with the procedure which was performed because of their increased risk of breast cancer.
在六年时间里，针对高危情况进行了163例预防性皮下乳房切除术。对所有病例评估了即刻手术并发症，并随访至少五年。皮下乳房切除术后无论是否同时进行皮肤缩减，术后并发症包括血肿、感染、乳头区域坏死、疼痛和感觉障碍。最显著的长期并发症是中度至重度包膜形成。尽管存在这些问题，但大多数因乳腺癌风险增加而接受该手术的女性对手术效果感到满意。
