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SF-36 量表评估类风湿关节炎患者的生活质量。

Quality of Life Assessment by SF-36 among the Patients with Rheumatoid Arthritis.

机构信息

Dr Md Mubdiur Rahman, Assistant Registrar, Physical Medicine and Rehabilitation, Mymensingh Medical College Hospital, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2022 Jul;31(3):586-591.

Abstract

Rheumatoid arthritis (RA) patients have substantial functional disability which poses a significant impact on the quality of life (QoL). So, this study aims to assess the QoL of RA patients by the Short Form Health Survey-36 (SF-36) questionnaire. Total sixty-two (62) rheumatoid arthritis patients were included in this cross-sectional observational study and were performed in the Department of Physical Medicine and Rehabilitation, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from August 2018 to September 2019 according to selection criteria. A Bengali validated version of Medical Outcomes Study-36: Item Short Form Health Survey (SF-36) questionnaire was used to assess QoL. Among the sixty-two (62) patients, mean age was 44.18±12.14 years with female preponderance (77.4%). About one-fifth of the patients (19.4%, n=12) were illiterate and the majority (71.0%, n=44) were housewives. Amongst all, 53.2% (n=33) had monthly family income >20,000 taka. Forty percent (n=25) had a disease duration of 1 to 5 years. According to Disease Activity Score Sheet 28 (DAS-28), 36(58.1%) patients had moderate disease activity and 26(41.9%) patients had high disease activity. Among the 8 domains, the mental health domain had the highest score (42.77±13.78) and the role physical domain had the lowest (35.89±15.43). Male, literate patients with higher income had relatively better QoL. Patients with prolonged disease, high disease activity and irregular taking of Disease Modifying Anti-Rheumatic Drugs (DMARDs) had poor quality of life. A significant negative correlation was present between SF-36 scores and the DAS-28 scores (r = -0.803, p<0.001). Rheumatoid arthritis had a relatively poor quality of life regarding both physical and mental health components, but the physical health component was predominantly affected.

摘要

类风湿关节炎(RA)患者存在显著的功能障碍,这对其生活质量(QoL)造成了重大影响。因此,本研究旨在通过健康调查简表 36 项(SF-36)问卷评估 RA 患者的 QoL。本横断面观察性研究共纳入 62 例类风湿关节炎患者,他们于 2018 年 8 月至 2019 年 9 月在孟加拉国达卡的 Bangabandhu Sheikh Mujib 医科大学(BSMMU)物理医学和康复系按照入选标准进行研究。采用孟加拉语验证版医学结局研究 36 项:短式健康调查(SF-36)问卷评估 QoL。在这 62 例患者中,平均年龄为 44.18±12.14 岁,女性居多(77.4%)。约五分之一的患者(19.4%,n=12)为文盲,大多数(71.0%,n=44)为家庭主妇。在所有患者中,53.2%(n=33)的家庭月收入超过 20,000 塔卡。40.0%(n=25)的患者病程为 1-5 年。根据疾病活动评分 28(DAS-28),36(58.1%)例患者处于中度疾病活动,26(41.9%)例患者处于高度疾病活动。在 8 个领域中,心理健康领域的评分最高(42.77±13.78),身体角色领域的评分最低(35.89±15.43)。男性、文化程度较高且收入较高的患者生活质量相对较好。病程较长、疾病活动度较高且不规律服用改善病情抗风湿药(DMARDs)的患者生活质量较差。SF-36 评分与 DAS-28 评分之间存在显著负相关(r=-0.803,p<0.001)。RA 患者在身心健康方面的生活质量均较差,但主要受身体功能健康的影响。

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