Cortés Sandra, Leiva Cinthya, Ojeda María José, Bustamante-Ara Natalia, Wambaa Wanjiku, Dominguez Alan, Pasten Salvo Carlos, Rodriguez Peralta Camila, Rojas Arenas Bárbara, Vargas Mesa Diego, Ahumada-Padilla Ericka
Department of Public Health, Pontificia Universidad Católica de Chile, Santiago, Chile.
Advanced Center for Chronic Diseases (ACCDIS), Pontificia Universidad Católica de Chile, Santiago, Chile.
Environ Health Insights. 2022 Jun 27;16:11786302221107136. doi: 10.1177/11786302221107136. eCollection 2022.
One recognized cause of cardiorespiratory diseases is air pollution. Older adults (OA) are one of the most vulnerable groups that suffer from its adverse effects. The objective of the study was to analyze the association between exposure to air pollution and changes in cardiorespiratory variables in OA. Observational prospective cohort study. Health questionnaires, blood pressure (BP) measurements, lung functions, respiratory symptoms, physical activity levels, and physical fitness in high and low exposure to air pollution were all methods used in evaluating OAs in communes with high contamination rates. Linear and logistic models were created to adjust for variables of interest. A total of 92 OA participated in this study. 73.9% of the subjects were women with 72.3 ± 5.6 years. 46.7% were obese, while 12.1% consumed tobacco. The most prevalent diseases found were hypertension, diabetes, and cardiovascular disease. Adjusted linear models maintained an increase for systolic BP of 6.77 mmHg (95% CI: 1.04-12.51), and diastolic of 3.51 mmHg (95% CI: 0.72-6.29), during the period of high exposure to air pollution. The adjusted logistic regression model indicated that, during the period of high exposure to air pollution increase the respiratory symptoms 4 times more (OR: 4.43, 95% CI: 2.07-10.04) in the OA. The results are consistent with an adverse effect on cardiorespiratory variables in periods of high exposure to air pollution in the OA population.
公认的心肺疾病病因之一是空气污染。老年人是受其不良影响的最脆弱群体之一。本研究的目的是分析空气污染暴露与老年人心肺变量变化之间的关联。观察性前瞻性队列研究。健康问卷、血压测量、肺功能、呼吸道症状、身体活动水平以及空气污染高暴露和低暴露情况下的身体素质,都是在污染率高的社区评估老年人时所采用的方法。创建线性和逻辑模型以调整相关变量。共有92名老年人参与了本研究。73.9%的受试者为女性,年龄为72.3±5.6岁。46.7%的人肥胖,12.1%的人吸烟。最常见的疾病是高血压、糖尿病和心血管疾病。调整后的线性模型显示,在空气污染高暴露期间,收缩压升高6.77 mmHg(95%置信区间:1.04 - 12.51),舒张压升高3.51 mmHg(95%置信区间:0.72 - 6.29)。调整后的逻辑回归模型表明,在空气污染高暴露期间,老年人出现呼吸道症状的几率增加4倍(比值比:4.43,95%置信区间:2.07 - 10.04)。研究结果与空气污染高暴露期间老年人群体心肺变量受到不良影响一致。