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Giant cell tumors of the sacrum: is non-operative treatment effective?骶骨巨细胞瘤:非手术治疗有效吗?
Eur Spine J. 2021 Oct;30(10):2881-2886. doi: 10.1007/s00586-020-06650-x. Epub 2020 Oct 26.
2
Excisional Curettage of Benign Cystic Lesions.良性囊性病变的切除刮除术
JBJS Essent Surg Tech. 2019 Jul 10;9(3):e24. doi: 10.2106/JBJS.ST.18.00036. eCollection 2019 Jul-Sep.
3
Neoadjuvant denosumab: its role and results in operable cases of giant cell tumour of bone.新辅助地舒单抗:其在可手术治疗的骨巨细胞瘤中的作用和结果。
Bone Joint J. 2019 Feb;101-B(2):170-177. doi: 10.1302/0301-620X.101B2.BJJ-2018-0907.R2.
4
Wide resection versus curettage in giant cell tumor with pathological fracture? A systematic review and meta-analysis.巨大细胞瘤合并病理性骨折时广泛切除与刮除术的比较?一项系统评价和荟萃分析。
J Clin Orthop Trauma. 2018 Mar;9(Suppl 1):S15-S18. doi: 10.1016/j.jcot.2017.07.007. Epub 2017 Jul 15.
5
How to Fill the Cavity after Curettage of Giant Cell Tumors around the Knee? A Multicenter Analysis.如何填充膝关节周围巨细胞瘤刮除术后的空腔?一项多中心分析。
Chin Med J (Engl). 2017 Nov 5;130(21):2541-2546. doi: 10.4103/0366-6999.217093.
6
Giant Cell Tumor of Bone - An Overview.骨巨细胞瘤——概述
Arch Bone Jt Surg. 2016 Jan;4(1):2-9.
7
Curettage and reconstruction by the sandwich technique for giant cell tumours around the knee.采用三明治技术对膝关节周围骨巨细胞瘤进行刮除与重建
J Orthop Surg (Hong Kong). 2014 Dec;22(3):351-5. doi: 10.1177/230949901402200317.
8
Survival of modern knee tumor megaprostheses: failures, functional results, and a comparative statistical analysis.现代膝关节肿瘤假体的生存率:失败情况、功能结果及比较性统计分析
Clin Orthop Relat Res. 2015 Mar;473(3):891-9. doi: 10.1007/s11999-014-3699-2.
9
Joint salvage using sandwich technique for giant cell tumors around knee.采用三明治技术对膝关节周围骨巨细胞瘤进行关节挽救术。
J Knee Surg. 2015 Apr;28(2):157-64. doi: 10.1055/s-0034-1373738. Epub 2014 Apr 21.
10
The clinical approach toward giant cell tumor of bone.骨巨细胞瘤的临床治疗方法。
Oncologist. 2014 May;19(5):550-61. doi: 10.1634/theoncologist.2013-0432. Epub 2014 Apr 9.

挽救不可挽救的骨巨细胞瘤:“纵向三明治技术”

Salvaging the Unsalvageable Giant Cell Tumors of Bone: The 'Longitudinal Sandwich Technique'.

作者信息

Poudel Rishi Ram, Tiwari Akshay, Jain Aakriti, Verma Vivek

机构信息

Division of Musculoskeletal Oncology, Department of Surgical Oncology, Nepal Cancer Hospital & Research Center, Lalitpur, Nepal.

Division of Musculoskeletal Oncology, Department of Surgical Oncology, Max Institute of Cancer Care, New Delhi, India.

出版信息

Indian J Surg Oncol. 2022 Jun;13(2):316-321. doi: 10.1007/s13193-022-01545-3. Epub 2022 May 6.

DOI:10.1007/s13193-022-01545-3
PMID:35782817
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9240147/
Abstract

Management of Campanacci Grade III Giant Cell Tumors of bone (GCT) is challenging. Although selected cases of Grade III GCTs can still be managed with intralesional extended curettage, wide excision of the lesion is usually recommended when there is extensive cortical destruction. This study describes the outcome of 'longitudinal sandwich technique' for extended curettage of Grade III GCTs with more than 50% cortical destruction. Here, the deficiency of cortex was made up for by using bone graft/graft substitute, used alongside cement placed in a longitudinal fashion. Twelve patients operated with this technique between Jan 2012 and Jan 2018 were reviewed. Majority of the lesions involved the lower limbs. Bone graft was used in eight whereas commercial bone graft substitute was used in the remaining four, along with bone cement in all. On follow-up ranging from 38 to 84 months (median follow-up 59 months), there were 4 local recurrences (33.33%). All recurrences were managed successfully with repeat surgery without the need for bony resection. Mean MSTS score during the last follow-up was 25.08 ± 2.31 and all patients were disease-free during the last follow-up. 'Longitudinal sandwich technique' helps to expand the indications of extended curettage even for aggressive Grade III GCTs, with satisfactory outcomes.

摘要

骨巨细胞瘤(GCT)Campanacci III级的治疗具有挑战性。尽管部分III级GCT病例仍可通过病灶内扩大刮除术进行治疗,但当出现广泛的皮质破坏时,通常建议对病变进行广泛切除。本研究描述了“纵向三明治技术”用于皮质破坏超过50%的III级GCT扩大刮除术的结果。在此,皮质缺损通过使用骨移植/移植替代物来弥补,同时纵向放置骨水泥。回顾了2012年1月至2018年1月间采用该技术手术的12例患者。大多数病变累及下肢。8例使用了骨移植,其余4例使用了商用骨移植替代物,均同时使用了骨水泥。随访时间为38至84个月(中位随访时间59个月),有4例局部复发(33.33%)。所有复发均通过再次手术成功处理,无需进行骨切除。最后一次随访时的平均MSTS评分为25.08±2.31,所有患者在最后一次随访时均无疾病。“纵向三明治技术”有助于扩大扩大刮除术的适应证,即使对于侵袭性III级GCT,也能取得满意的结果。