Gregersen P, Klausen H, Elsnab C U
Am J Ind Med. 1987;11(4):399-417. doi: 10.1002/ajim.4700110403.
On the basis of previous investigations from occupational medicine, neurology, and neuropyschology, a retrospective evaluation was made of 21 painters in whom chronic toxic encephalopathy following exposure to organic solvents had been diagnosed during a stay in the Neurology Department of Gentofte Hospital, Copenhagen, in the period 1976-1980. All the painters had given up their jobs for this reason. The assumption of a causal relationship between the exposure and the intellectual impairment was supported by a possible dose-effect relationship. The chronic toxic symptoms had considerable social consequences. Five years later, ten had not gotten other jobs. The lack of working ability was correlated to advancing age, increasing exposure, and increasing intellectual impairment. According to the results of the study, conditions at work places ought to be changed in such a way that harmful exposure can be prevented in the future.
根据职业医学、神经学和神经心理学先前的调查，对1976年至1980年期间在哥本哈根根措夫特医院神经科住院期间被诊断为接触有机溶剂后患有慢性中毒性脑病的21名油漆工进行了回顾性评估。所有这些油漆工都因此放弃了工作。接触与智力损害之间存在因果关系的假设得到了可能的剂量效应关系的支持。慢性中毒症状产生了相当大的社会后果。五年后，有十人没有找到其他工作。工作能力的缺乏与年龄增长、接触增加和智力损害加重相关。根据研究结果，工作场所的条件应该改变，以便将来能够预防有害接触。
