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对接触低水平溶剂的油漆工剂量相关神经行为效应的调查。

Investigation of dose related neurobehavioural effects in paintmakers exposed to low levels of solvents.

作者信息

Spurgeon A, Glass D C, Calvert I A, Cunningham-Hill M, Harrington J M

机构信息

Institute of Occupational Health, University of Birmingham, Edgbaston.

出版信息

Occup Environ Med. 1994 Sep;51(9):626-30. doi: 10.1136/oem.51.9.626.

DOI:10.1136/oem.51.9.626
PMID:7951795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1128057/
Abstract

A cross sectional study was carried out to compare 110 paintmakers exposed to solvents with 110 age matched controls for outcome measures designed to assess cognitive performance and mental health. Hygiene data available for the paintmakers allowed the development of individual indices of solvent exposure and the analyses of health effects in relation to both duration and intensity of exposure. No effects on cognitive functioning or mental health were found in the paintmakers. For most of their period of employment the exposure of the paintmakers had been below current occupational exposure limits. The results are therefore interpreted as providing support for the view that long term exposure at or below current compliance levels does not result in damage to the central nervous system.

摘要

开展了一项横断面研究,将110名接触溶剂的油漆工与110名年龄匹配的对照组人员进行比较,以评估旨在衡量认知表现和心理健康的各项指标。油漆工的卫生数据有助于制定个体溶剂接触指数,并分析与接触持续时间和强度相关的健康影响。未发现油漆工的认知功能或心理健康受到影响。在其就业的大部分时间里,油漆工的接触水平一直低于当前职业接触限值。因此,这些结果被解释为支持以下观点:在当前合规水平或以下的长期接触不会导致中枢神经系统受损。

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本文引用的文献

1
Retrospective assessment of solvent exposure in paint manufacturing.油漆制造中溶剂暴露的回顾性评估。
Occup Environ Med. 1994 Sep;51(9):617-25. doi: 10.1136/oem.51.9.617.
2
Physiological, motivational, and cognitive effects of aircraft noise on children: moving from the laboratory to the field.飞机噪音对儿童的生理、动机和认知影响:从实验室走向实际环境
Am Psychol. 1980 Mar;35(3):231-43. doi: 10.1037//0003-066x.35.3.231.
3
Psychological function changes among maintenance house painters exposed to low levels of organic solvent mixtures.接触低水平有机溶剂混合物的维修油漆工心理功能变化
Acta Psychiatr Scand Suppl. 1983;303:81-91. doi: 10.1111/j.1600-0447.1983.tb00944.x.
4
A computer-administered neurobehavioral evaluation system for occupational and environmental epidemiology. Rationale, methodology, and pilot study results.一种用于职业与环境流行病学的计算机管理神经行为评估系统。原理、方法及初步研究结果。
J Occup Med. 1985 Mar;27(3):206-12.
5
The combined effects of occupational health hazards: an experimental investigation of the effects of noise, nightwork and meals.职业健康危害的综合影响:噪声、夜班和饮食影响的实验研究
Int Arch Occup Environ Health. 1987;59(1):83-9. doi: 10.1007/BF00377682.
6
Chronic toxic encephalopathy in solvent-exposed painters in Denmark 1976-1980: clinical cases and social consequences after a 5-year follow-up.1976 - 1980年丹麦接触溶剂的油漆工慢性中毒性脑病:5年随访后的临床病例及社会后果
Am J Ind Med. 1987;11(4):399-417. doi: 10.1002/ajim.4700110403.
7
Neurobehavioural effects of occupational exposure to organic solvents among construction painters.建筑油漆工职业接触有机溶剂的神经行为效应
Br J Ind Med. 1987 May;44(5):292-308. doi: 10.1136/oem.44.5.292.
8
Neurobehavioral effects of solvents in construction painters.建筑油漆工接触溶剂的神经行为效应
J Occup Med. 1988 Feb;30(2):116-23.
9
Cross-sectional epidemiological study on neurotoxicity of solvents in paints and lacquers.
Int Arch Occup Environ Health. 1988;60(4):233-41. doi: 10.1007/BF00378470.
10
Neurobehavioral effects of long-term occupational exposure to organic solvents: two comparable studies.长期职业性接触有机溶剂的神经行为效应:两项可比研究。
Am J Ind Med. 1992;22(3):325-35. doi: 10.1002/ajim.4700220306.