Gade A, Mortensen E L, Bruhn P
Department of Neurology, Rigshospitalet, Copenhagen, Denmark.
Acta Neurol Scand. 1988 Apr;77(4):293-306. doi: 10.1111/j.1600-0404.1988.tb05913.x.
Twenty solvent-exposed workers, most of them painters, had been diagnosed as cases of toxic encephalopathy in 1978/79. Two years later they were re-examined with an extensive battery of neuropsychological tests. Their performance was unchanged on retesting. We have now compared their test results with those of non-exposed control subjects. Previous impressions of significant intellectual impairment in the solvent-exposed patients could not be confirmed when the influence of age, education, and intelligence was taken into consideration. The present group with presumed toxic encephalopathy is assumed to be representative of other patients who were similarly diagnosed in our department. The presently reanalyzed cases had been diagnosed as brain damaged and reported as such in the literature. Thus, they may have contributed to the formation of the concept of the "chronic painters' syndrome" with dementia.
1978/79年,20名接触溶剂的工人(其中大部分是油漆工)被诊断为中毒性脑病患者。两年后,他们接受了一系列广泛的神经心理学测试复查。复测时他们的表现没有变化。我们现在将他们的测试结果与未接触溶剂的对照受试者的结果进行了比较。当考虑到年龄、教育程度和智力的影响时,之前关于接触溶剂患者存在明显智力损害的印象无法得到证实。目前这组被认为患有中毒性脑病的患者被假定为在我们科室被类似诊断的其他患者的代表。目前重新分析的病例曾被诊断为脑损伤,并在文献中如此报道。因此,他们可能促成了伴有痴呆的“慢性油漆工综合征”这一概念的形成。