Hato Hiroyuki, Sakata Ken-Ichiro, Sato Jun, Hasebe Akira, Yamazaki Yutaka, Kitagawa Yoshimasa
Oral Diagnosis and Medicine, Faculty of Dental Medicine, Hokkaido University, Sapporo, Japan.
Department of Oral Molecular Microbiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
J Dent Sci. 2022 Jul;17(3):1458-1461. doi: 10.1016/j.jds.2021.10.020. Epub 2021 Nov 30.
This study aimed to determine the factors associated with the co-infection of and . This retrospective study conducted between January 2015 and 2020 comprised 131 patients who were diagnosed with oral candidiasis. The factors associated with this condition were analyzed by univariate and multivariate logistic regression. Age and denture use were identified as significant risk factors in the univariate analysis. The multivariate logistic regression analysis revealed that denture use (odds ratio [OR], 8.44 95% confidence interval [CI], 1.99-28.3) and immunosuppressive therapy (OR, 9.20; 95% CI, 1.19-62.0) had significant effects on co-infection with the two species. These findings suggest that immunosuppressive therapy using and dentures is significantly associated with oral candidiasis caused by co-infection of and .
本研究旨在确定与[两种未提及的物种名称]合并感染相关的因素。这项在2015年1月至2020年期间进行的回顾性研究纳入了131例被诊断为口腔念珠菌病的患者。通过单因素和多因素逻辑回归分析与该疾病相关的因素。年龄和义齿使用在单因素分析中被确定为显著风险因素。多因素逻辑回归分析显示,义齿使用(比值比[OR],8.44;95%置信区间[CI],1.99 - 28.3)和免疫抑制治疗(OR,9.20;95%CI,1.19 - 62.0)对两种[物种名称]合并感染有显著影响。这些发现表明,使用[未提及的物质名称]和义齿进行免疫抑制治疗与由[两种未提及的物种名称]合并感染引起的口腔念珠菌病显著相关。