El-Sakhawy Mohamed A, El-Sehrawy Mohamed Gamal, Waggiallah Hisham Ali, Ibrahim Ateya Megahed, Ateya Abeer Ali El-Sherbiny
Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Department of Medicinal and Aromatic Plants, Desert Research Center, Cairo, Egypt.
Saudi J Biol Sci. 2023 Jun;30(6):103657. doi: 10.1016/j.sjbs.2023.103657. Epub 2023 Apr 23.
Cigarette smoking is regarded as a major global health risk, therefore the aim of this work was to investigate the association of oral spp. as one of the etiological agents of denture stomatitis with smokers of cigarette, hookah (shisha), and electronic smoking, also a dose-response relationship between the duration of smoking and the probability of denture stomatitis between volunteers. Oral rinse samples were collected from 47 male volunteers including 34 smokers and 13 non-smokers, also data of volunteers were collected via a questionnaire forum. Patterns of smoking were shown that smokers using tobacco cigarettes 17 (36.2 %), electronic cigarettes 16 (34.04 %), and hookah smokers 8 (17.02 %). A comparison of smokers and non-smokers regarding effects on oral health showed significantly finding (P < 0.05) indicating that smoking affects oral health in all evaluated parameters (an oral mucosal abnormality, mouth ulcers, bad breath, and feeling of dry mouth). Out of 19 Candida isolates, 18 (94.7 %) were identified as Candida albicans and 1 (5.3 %) as Candida tropicalis. Among the volunteers who presented with oral Candida (19 volunteers), 17 (89.5%) were smokers, while non-smoker volunteers were 2 (10.5 %), so it can be concluded that smoking was a significant positive correlation to the presence of Candida in the oral cavity. Five volunteers suffered from chronic diseases; 4 (8.5%) diabetes mellitus and 1 (2.1%) anemia as a systemic predisposing factor for oropharyngeal infection. Amphotericin and Nystatin had varying degrees of activity against isolated Candida isolates.
吸烟被视为全球主要的健康风险，因此本研究的目的是调查口腔菌种作为义齿性口炎的病因之一与香烟、水烟和电子烟吸烟者之间的关联，以及志愿者中吸烟持续时间与义齿性口炎发生概率之间的剂量反应关系。从47名男性志愿者中收集口腔冲洗样本，其中包括34名吸烟者和13名非吸烟者，同时通过问卷调查收集志愿者的数据。吸烟模式显示，吸香烟者17人（36.2%），吸电子烟者16人（34.04%），吸水烟者8人（17.02%）。吸烟者和非吸烟者对口腔健康影响的比较显示出显著差异（P<0.05），表明吸烟在所有评估参数（口腔黏膜异常、口腔溃疡、口臭和口干感）上都会影响口腔健康。在19株念珠菌分离株中，18株（94.7%）被鉴定为白色念珠菌，1株（5.3%）为热带念珠菌。在出现口腔念珠菌的志愿者（19名志愿者）中，17名（89.5%）是吸烟者，而非吸烟者志愿者为2名（10.5%），因此可以得出结论，吸烟与口腔念珠菌的存在呈显著正相关。5名志愿者患有慢性病；4名（8.5%）患有糖尿病，1名（2.1%）患有贫血，这是口咽感染的全身易感因素。两性霉素和制霉菌素对分离出的念珠菌分离株有不同程度的活性。
