Weinstein Y
Mech Ageing Dev. 1978 Jul;8(1):63-8. doi: 10.1016/0047-6374(78)90007-6.
Pituitary and serum levels of LH and FSH and hypothalamic GnRH content were measured in acyclic, congenitally athymic (nu/nu) female mice. No significant differences were found between athymic and normal dioestrous mice of the same age (3 months). The serum LH level of the athymic mouse failed to increase 6 days after ovariectomy, but increased in response to injection of GnRH. The results suggest that the athymic nude mice suffer from impairment of hypothalamic control of the pituitary.
对处于非发情周期、先天性无胸腺（nu/nu）的雌性小鼠测量了垂体和血清中促黄体生成素（LH）和促卵泡生成素（FSH）的水平以及下丘脑促性腺激素释放激素（GnRH）的含量。在相同年龄（3个月）的无胸腺小鼠和正常处于间情期的小鼠之间未发现显著差异。无胸腺小鼠在卵巢切除术后6天血清LH水平未能升高，但在注射GnRH后升高。结果表明，无胸腺裸鼠存在下丘脑对垂体控制的损害。
