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人类因感染鲑科鱼类身上的鲑居尾孢虫而引发肠道感染。

Human intestinal infection with Nanophyetus salmincola from salmonid fishes.

作者信息

Eastburn R L, Fritsche T R, Terhune C A

出版信息

Am J Trop Med Hyg. 1987 May;36(3):586-91. doi: 10.4269/ajtmh.1987.36.586.

DOI:10.4269/ajtmh.1987.36.586
PMID:3578655
Abstract

Between 1974 and 1985, 10 patients were studied who presented with either gastrointestinal complaints or unexplained peripheral blood eosinophilia, and had eggs typical for N. salmincola recovered from their stools. Clinical findings in 8 of the 10 included increased frequency of bowel movements or diarrhea (6), peripheral blood eosinophilia (6), abdominal discomfort (5), nausea and vomiting (3), weight loss (2), and fatigue (2). Two were asymptomatic. Eight recalled eating fish prior to the onset of symptoms. Anthelminthic treatment consisting of three 2-g doses of niclosamide (2 patients) or two 50 mg/kg doses of bithionol (1 patient) proved effective. In the remaining individuals symptoms resolved slowly over several months.

摘要

1974年至1985年间,对10例患者进行了研究,这些患者表现出胃肠道不适或不明原因的外周血嗜酸性粒细胞增多,且粪便中发现了典型的鲑居尾孢虫虫卵。10例患者中的8例临床症状包括排便次数增加或腹泻(6例)、外周血嗜酸性粒细胞增多(6例)、腹部不适(5例)、恶心和呕吐(3例)、体重减轻(2例)以及疲劳(2例)。2例无症状。8例患者回忆起在症状出现前曾食用过鱼。由3剂2克氯硝柳胺(2例患者)或2剂50毫克/千克硫双二氯酚(1例患者)组成的驱虫治疗被证明是有效的。其余患者的症状在几个月内缓慢缓解。

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