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Genetic variant rs9848497 up-regulates expression, thereby influencing leadership phenotypes.

作者信息

Qiu Shizheng, Hu Yang, Zou Quan, Liu Guiyou

机构信息

School of Computer Science and Technology, Harbin Institute of Technology, Harbin 150001, China.

Yangtze Delta Region Institute (Quzhou), University of Electronic Science and Technology of China, Quzhou 313001, China.

出版信息

Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2207847119. doi: 10.1073/pnas.2207847119. Epub 2022 Jul 5.

DOI:10.1073/pnas.2207847119
PMID:35787185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9303931/
Abstract
摘要

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本文引用的文献

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Genetics, leadership position, and well-being: An investigation with a large-scale GWAS.遗传、领导地位和幸福感:一项基于大规模 GWAS 的研究。
Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2114271119. doi: 10.1073/pnas.2114271119. Epub 2022 Mar 14.
2
MST1-knockdown protects against impairment of working memory via regulating neural activity in depression-like mice.MST1 敲低通过调节抑郁样小鼠的神经活动保护工作记忆损伤。
Genes Brain Behav. 2022 Feb;21(2):e12782. doi: 10.1111/gbb.12782. Epub 2022 Jan 19.
3
Down-regulation of MST1 in hippocampus protects against stress-induced depression-like behaviours and synaptic plasticity impairments.下调海马中的 MST1 可预防应激诱导的抑郁样行为和突触可塑性损伤。
Brain Behav Immun. 2021 May;94:196-209. doi: 10.1016/j.bbi.2021.02.007. Epub 2021 Feb 17.
4
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets.GWAS 和 eQTL 研究汇总数据的整合预测复杂性状的基因靶点。
Nat Genet. 2016 May;48(5):481-7. doi: 10.1038/ng.3538. Epub 2016 Mar 28.
5
Integrative approaches for large-scale transcriptome-wide association studies.大规模全转录组关联研究的综合方法
Nat Genet. 2016 Mar;48(3):245-52. doi: 10.1038/ng.3506. Epub 2016 Feb 8.
6
The role of regulatory variation in complex traits and disease.调控变异在复杂性状和疾病中的作用。
Nat Rev Genet. 2015 Apr;16(4):197-212. doi: 10.1038/nrg3891. Epub 2015 Feb 24.
7
Identification of common genetic variants controlling transcript isoform variation in human whole blood.人类全血中控制转录本异构体变异的常见遗传变异的鉴定。
Nat Genet. 2015 Apr;47(4):345-52. doi: 10.1038/ng.3220. Epub 2015 Feb 16.
8
Correlative gene expression pattern linking RNF123 to cellular stress-senescence genes in patients with depressive disorder: implication of DRD1 in the cerebral cortex.将 RNF123 与抑郁症患者细胞应激衰老基因相关的基因表达模式:大脑皮层中 DRD1 的作用。
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