Department of Management and Organization, National University of Singapore, 119245, Singapore.
Department of Management, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2114271119. doi: 10.1073/pnas.2114271119. Epub 2022 Mar 14.
SignificanceOur study presents the largest whole-genome investigation of leadership phenotypes to date. We identified genome-wide significant loci for leadership phenotypes, which are overlapped with top hits for bipolar disorder, schizophrenia, and intelligence. Our study demonstrated the polygenetic nature of leadership, the positive genetic correlations between leadership traits and a broad range of well-being indicators, and the unique association of leadership with well-being after accounting for genetic influences related to other socioeconomic status measures. Our findings offer insights into the biological underpinnings of leadership.
意义
本研究是迄今为止针对领导特质进行的最大规模的全基因组研究。我们确定了与双相情感障碍、精神分裂症和智力相关的领导特质的全基因组显著位点。本研究证明了领导特质的多基因性质，领导特质与广泛的幸福感指标之间存在正的遗传相关性，以及在考虑与其他社会经济地位衡量标准相关的遗传影响后，领导特质与幸福感之间的独特关联。我们的发现为领导特质的生物学基础提供了新的见解。
