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一种旨在减少过敏性接触性皮炎和头发损伤的永久性染发剂的临床评估。

A clinical evaluation of a permanent hair dye designed to reduce allergic contact dermatitis and hair damage.

机构信息

Dermatology Consulting Services, PLLC, High Point, North Carolina, USA.

出版信息

J Cosmet Dermatol. 2022 Sep;21(9):3925-3928. doi: 10.1111/jocd.15212. Epub 2022 Jul 19.

DOI:10.1111/jocd.15212
PMID:35790071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9796119/
Abstract

BACKGROUND

Permanent hair dye is the most commonly used anti-aging procedure used by both men and women. However, permanent hair dye can cause irritant contact dermatitis due to ammonia and allergic contact dermatitis due to paraphylenediamine (PPD).

METHODS

This research examined an ammonia-free and PPD-free permanent hair dye in 50 ethnically diverse females 21-91 years of age who were current users of permanent hair dyes. Subjects were patch tested prior to dyeing. Two dye sessions were undertaken at baseline and 2-6 weeks post-baseline depending on the dyeing habits of the subject.

RESULTS

50/50 subjects successfully completed the study with no incidence of allergic or irritant contact dermatitis. After 2 dyeing procedures, the dermatologists rated an 87% improvement in hair shine, 90% improvement in hair color, 88% improvement in hair moisturization, 87% improvement in hair porosity, and 88% improvement in hair combability.

CONCLUSIONS

A MEA-based ammonia-free cream hair color without PPD or resorcinol was safe for use on the hair and scalp of females with diverse hair types and textures.

摘要

背景

永久性染发剂是男性和女性最常使用的抗衰老程序。然而,永久性染发剂可因氨而引起刺激性接触性皮炎,因对苯二胺(PPD)而引起过敏性接触性皮炎。

方法

本研究在 50 名种族多样化的女性中进行,这些女性年龄在 21-91 岁之间,她们是永久性染发剂的当前使用者。在染发前进行斑贴试验。根据受试者的染发习惯,在基线和基线后 2-6 周进行两次染发。

结果

50/50 的受试者成功完成了研究,没有发生过敏性或刺激性接触性皮炎。经过 2 次染发程序后,皮肤科医生评估头发光泽改善了 87%,头发颜色改善了 90%,头发保湿改善了 88%,头发多孔性改善了 87%,头发梳理性改善了 88%。

结论

一种基于 MEA 的无氨乳膏状染发剂,不含 PPD 或间苯二酚,对具有不同发质和纹理的女性的头发和头皮使用是安全的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fe4/9796119/9b5319646181/JOCD-21-3925-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fe4/9796119/9b5319646181/JOCD-21-3925-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fe4/9796119/9b5319646181/JOCD-21-3925-g001.jpg

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本文引用的文献

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para-Phenylenediamine: the profile of an important allergen. Results of the IVDK.对苯二胺:一种重要过敏原的概况。IVDK的结果。
Br J Dermatol. 2008 Aug;159(2):379-86. doi: 10.1111/j.1365-2133.2008.08644.x. Epub 2008 May 28.
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p-Phenylenediamine.对苯二胺
Dermatitis. 2006 Jun;17(2):53-5.
Curr Pediatr Rev. 2024;20(4):478-488. doi: 10.2174/1573396320666230626122135.
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A comparison of dyeing efficacy between hair-oxidation-based and hair-coating-based shampoos for the treatment of gray hair.氧化型染发剂与发用涂料型洗发水治疗白发效果的比较。
Skin Res Technol. 2023 Jun;29(6):e13383. doi: 10.1111/srt.13383.