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儿科心胸血管炎:多模态影像学综述。

Pediatric cardiothoracic vasculitis: multimodality imaging review.

机构信息

Department of Radiology, Stanford University School of Medicine, 725 Welch Road, Stanford, CA, 94305, USA.

出版信息

Pediatr Radiol. 2022 Sep;52(10):1895-1909. doi: 10.1007/s00247-022-05431-6. Epub 2022 Jul 6.

Abstract

The pediatric vasculitides are a relatively uncommon and heterogeneous group of disorders characterized by vessel inflammation, often with cardiothoracic involvement. Diagnosis and monitoring are often clinically challenging because of the nonspecific symptoms and laboratory markers. Thus, imaging has assumed increasing importance for early detection of disease activity, extent and complications as well as long-term monitoring pre- and post-treatment. Herein, we review the major pediatric vasculitides with frequent chest manifestations, including Takayasu arteritis, Kawasaki disease, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis, microscopic polyangiitis, Behçet disease and potential mimics. We highlight key clinical features and management considerations, emphasizing the central role of imaging.

摘要

儿科血管炎是一组相对罕见且异质性的疾病,其特征为血管炎症,常伴有心胸器官受累。由于症状和实验室标志物无特异性,诊断和监测通常具有临床挑战性。因此,影像学对于早期发现疾病活动、范围和并发症以及治疗前后的长期监测变得越来越重要。在此,我们回顾了伴有频繁胸部表现的主要儿科血管炎,包括 Takayasu 动脉炎、川崎病、肉芽肿性多血管炎、嗜酸性肉芽肿性多血管炎、显微镜下多血管炎、贝赫切特病和潜在的类似疾病。我们强调了关键的临床特征和管理注意事项,影像学发挥着核心作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/daff/9256530/05ece65d88b1/247_2022_5431_Fig1_HTML.jpg

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