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抑郁和暴食在不良童年经历(ACEs)与肥胖关系中的作用。

The Roles of Depression and Binge Eating in the Relationship Between Adverse Childhood Experiences (ACEs) and Obesity.

机构信息

School of Social Work, West Virginia University, PO Box 6830, Morgantown, WV, 26506, USA.

Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, WV, USA.

出版信息

Obes Surg. 2022 Sep;32(9):3034-3040. doi: 10.1007/s11695-022-06192-9. Epub 2022 Jul 5.

Abstract

OBJECTIVE

Research has demonstrated that adverse childhood experiences (ACEs) were related to elevated lifetime risk of developing obesity, but the underlying mechanisms between ACEs and development of obesity are yet to be fully elucidated. The current study aims to extend exiting evidence on underlying mechanisms between ACEs and development of obesity by examining whether depressive symptom and binge eating symptom have independently significant mediating effects on the association.

METHODS

The study used data from a total of 473 patients seeking bariatric surgery who completed psychological evaluation including ACEs, depressive symptom, and binge eating scale as a part of presurgical multidisciplinary weight management consultations. Mediation analyses were conducted using the PROCESS macro for SPSS to examine the research objective.

RESULTS

The study found that depressive symptom uniquely mediated the relationship between ACEs and obesity, but binge eating symptom did not significantly mediate the relationship independently of depression.

CONCLUSIONS

The unique role of depression in relation to childhood trauma in this study argues for more focus on a mental health intervention with bariatric patients during the preoperative period. Addressing ACEs for bariatric patients who present psychiatric symptoms during preoperative process could have potential benefits to patient care.

摘要

目的

研究表明,不良的童年经历(ACEs)与肥胖的终身风险升高有关,但 ACEs 与肥胖发展之间的潜在机制仍未完全阐明。本研究旨在通过检查抑郁症状和暴食症状是否对关联具有独立的显著中介作用,从而扩展 ACEs 与肥胖发展之间潜在机制的现有证据。

方法

该研究使用了总共 473 名接受减肥手术的患者的数据,这些患者在接受减肥手术前完成了心理评估,包括 ACEs、抑郁症状和暴食量表,作为多学科减肥管理咨询的一部分。使用 SPSS 的 PROCESS 宏进行中介分析,以检验研究目标。

结果

研究发现,抑郁症状在 ACEs 和肥胖之间的关系中具有独特的中介作用,但暴食症状在不考虑抑郁的情况下,独立中介作用不显著。

结论

本研究中抑郁在与童年创伤的关系中的独特作用表明,在术前期间,肥胖患者的心理健康干预应更加关注。在术前过程中出现精神症状的肥胖患者中,解决 ACEs 问题可能对患者护理有潜在益处。

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