Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
J Cosmet Dermatol. 2022 Nov;21(11):5931-5937. doi: 10.1111/jocd.15213. Epub 2022 Jul 19.
Follicular unit extraction (FUE) is a minimally invasive surgery that is becoming popular in hair restoration in cicatricial alopecia (CA).
Evaluation of FUE with or without platelet rich plasma (PRP) in scarring alopecia.
Twenty patients with CA were randomized into two groups. Group A (10 patients) underwent FUE, group B (10 patients) underwent FUE + PRP. PRP was injected 1 week before surgery, then monthly after surgery for 3 months. Follow up was done after 3, 6 and 12 months by calculating the density of surviving follicular units and the survival rate.
In group A, there was statistically significant increase in mean survival rate which was 30.30%. At 3 months, 67.26% at 6 months and 78.15% at 12 months. In group B, there was a significant increase in mean survival rate being 30.14% at 3 months, 58.75% at 6 months and 69.74% at 12 months. There was no significant difference between both groups at anytime during follow up period.
Follicular unit extraction is a preferred procedure for hair restoration in CA with few side effects. The role of PRP in HT is controversial. In the present study, PRP does not significantly affect the survival rate of hair grafts.
毛囊单位提取（FUE）是一种微创外科手术，在瘢痕性脱发（CA）的毛发修复中越来越受欢迎。
评估 FUE 联合或不联合富血小板血浆（PRP）在瘢痕性脱发中的应用。
20 例 CA 患者随机分为两组。A 组（10 例）行 FUE，B 组（10 例）行 FUE+PRP。PRP 在术前 1 周内注射，然后在术后每月注射 3 个月。在术后 3、6 和 12 个月通过计算存活毛囊单位的密度和存活率进行随访。
A 组的平均存活率有统计学显著增加，为 30.30%。在 3 个月时为 67.26%，在 6 个月时为 78.15%，在 12 个月时为 78.15%。B 组的平均存活率有显著增加，在 3 个月时为 30.14%，在 6 个月时为 58.75%，在 12 个月时为 69.74%。在整个随访期间，两组之间没有统计学差异。
毛囊单位提取是 CA 毛发修复的首选方法，副作用少。PRP 在 HT 中的作用存在争议。在本研究中，PRP 对毛发移植成活率无显著影响。
