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[特殊部位伤口愈合与瘢痕修复中的毛发移植]

[Hair transplantation in wound healing and scar repair in special areas].

作者信息

Huang Zhewei, Qian Xifei, Xu Yanwen, Kaindi Samuel Tumaini, Pakaya Collins Daniel, Zhang Jufang

机构信息

Fourth Clinical Medical College Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou Zhejiang, 310013, P. R. China.

Department of Medical Beauty, Hangzhou First People's Hospital Affiliated to Medical College of West Lake University, Hangzhou Zhejiang, 310006, P. R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 May 15;39(5):647-654. doi: 10.7507/1002-1892.202502051.

Abstract

OBJECTIVE

To review recent advances in the application of hair transplantation in wound healing and scar repair in special areas.

METHODS

An extensive review of the literature on the application of hair transplantation in wound healing and scar repair in special areas was conducted, focusing on cellular functions, molecular mechanisms, and clinical applications.

RESULTS

Hair transplantation has been shown to effectively promote wound healing and scar repair in special areas. The underlying mechanisms are complex, but current understanding emphasizes a strong association with hair follicle-associated stem cells (including epidermal stem cells, dermal papilla cells, dermal sheath cells, ).

CONCLUSION

The application of hair transplantation in wound healing and scar repair in special areas remains in its early stages. Further investigation into its mechanisms of action is essential, and randomized controlled trials are needed to establish its efficacy.

摘要

目的

综述毛发移植在特殊部位伤口愈合及瘢痕修复中的应用进展。

方法

广泛回顾毛发移植在特殊部位伤口愈合及瘢痕修复应用的文献,重点关注细胞功能、分子机制及临床应用。

结果

已证实毛发移植可有效促进特殊部位的伤口愈合及瘢痕修复。其潜在机制复杂,但目前的认识强调与毛囊相关干细胞(包括表皮干细胞、毛乳头细胞、毛鞘细胞)密切相关。

结论

毛发移植在特殊部位伤口愈合及瘢痕修复中的应用仍处于早期阶段。进一步研究其作用机制至关重要,且需要进行随机对照试验以确定其疗效。

相似文献

1
[Hair transplantation in wound healing and scar repair in special areas].[特殊部位伤口愈合与瘢痕修复中的毛发移植]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 May 15;39(5):647-654. doi: 10.7507/1002-1892.202502051.
2
[Research progress of hair follicle and related stem cells in scar-free wound healing].毛囊及相关干细胞在无瘢痕伤口愈合中的研究进展
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2021 Feb 15;35(2):241-245. doi: 10.7507/1002-1892.202005086.
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Hair Follicle Transplantation for Wound Repair.毛发移植修复创面。
Adv Wound Care (New Rochelle). 2021 Mar;10(3):153-163. doi: 10.1089/wound.2019.1139. Epub 2020 Jun 10.
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Are hair follicle stem cells promising candidates for wound healing?毛囊干细胞是否是伤口愈合的有前途的候选者?
Expert Opin Biol Ther. 2019 Feb;19(2):119-128. doi: 10.1080/14712598.2019.1559290. Epub 2019 Jan 7.

本文引用的文献

7
Breakthrough treatments for accelerated wound healing.突破性疗法加速伤口愈合。
Sci Adv. 2023 May 19;9(20):eade7007. doi: 10.1126/sciadv.ade7007. Epub 2023 May 17.
8
Aging of hair follicle stem cells and their niches.毛囊干细胞及其龛的衰老。
BMB Rep. 2023 Jan;56(1):2-9. doi: 10.5483/BMBRep.2022-0183.

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