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Head-to-head comparisons of the neutralizing antibody against SARS-CoV-2 variants elicited by four priming-boosting regimens.

作者信息

Jiang Hu-Dachuan, Guo Xi-Ling, Jin Peng-Fei, Tang Rong, Li Jing-Xin, Zhu Feng-Cai

机构信息

School of Public Health, Southeast University, Nanjing, People's Republic of China.

NHC Key laboratory of Enteric Pathogenic Microbiology(Jiangsu Provincial Center for Disease Control and Prevention), Nanjing, People's Republic of China.

出版信息

Emerg Microbes Infect. 2022 Dec;11(1):1751-1753. doi: 10.1080/22221751.2022.2095931.

DOI:10.1080/22221751.2022.2095931
PMID:35791773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9291705/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de96/9291705/7cfdfa024b10/TEMI_A_2095931_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de96/9291705/7cfdfa024b10/TEMI_A_2095931_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de96/9291705/7cfdfa024b10/TEMI_A_2095931_F0001_OC.jpg

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Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial.异源 AD5-nCOV 加科兴疫苗与同源科兴疫苗接种:一项随机 4 期试验。
Nat Med. 2022 Feb;28(2):401-409. doi: 10.1038/s41591-021-01677-z. Epub 2022 Jan 27.
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Heterologous versus homologous COVID-19 booster vaccination in previous recipients of two doses of CoronaVac COVID-19 vaccine in Brazil (RHH-001): a phase 4, non-inferiority, single blind, randomised study.
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Lancet. 2022 Feb 5;399(10324):521-529. doi: 10.1016/S0140-6736(22)00094-0. Epub 2022 Jan 21.
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Recombinant protein subunit vaccine booster following two-dose inactivated vaccines dramatically enhanced anti-RBD responses and neutralizing titers against SARS-CoV-2 and Variants of Concern.两剂灭活疫苗后接种重组蛋白亚单位疫苗加强针可显著增强针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)及其关注变异株的抗受体结合域(RBD)反应和中和效价。
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