Xie Zhao-Yun, Li Yuan-Jun, Lei Cong-Rong
Emergency Department, the Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou 558000,China.
Department of Obstetrics and Gynecology, the Third Affiliated Hospital of Guizhou Medical University,Duyun,Guizhou 558000,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2022 Jun;44(3):398-402. doi: 10.3881/j.issn.1000-503X.14368.
Objective To reveal the relationship between asymptomatic bacteriuria (ASB) and vaginal colonization of group B in the third trimester of pregnancy.Methods A total of 4287 pregnant women who were followed up from January 2018 to June 2021 were enrolled in this study.The pregnant women with ASB were assigned as the observation group,and those without ASB were matched at a ratio of 1∶4 as the control group.Results Among the 4287 pregnant women,158 (3.69%) pregnant women had ASB,including 28 (17.72%) with group B colonization in the third trimester.Among the 632 pregnant women without ASB (control),44 cases (6.96%) had vaginal colonization of group B in the third trimester.The colonization rate of group B in the pregnant women with ASB was significantly higher than that in the pregnant women without ASB (=17.666,<0.001).Logistic regression showed that ASB was positively correlated with the vaginal colonization of group B in the third trimester of pregnancy (=2.577,95%=1.509-4.402,=0.001).Conclusions ASB is positively correlated with the vaginal colonization of group B in the third trimester.The screening,prevention,and control of ASB in the early trimester is of great significance to reduce the vaginal colonization of group B in the third trimester.
目的 揭示妊娠晚期无症状菌尿（ASB）与B族阴道定植之间的关系。方法 选取2018年1月至2021年6月随访的4287例孕妇纳入本研究。将ASB孕妇作为观察组，无ASB孕妇按1∶4比例匹配作为对照组。结果 4287例孕妇中，158例（3.69%）有ASB，其中28例（17.72%）在妊娠晚期有B族定植。632例无ASB孕妇（对照组）中，44例（6.96%）在妊娠晚期有B族阴道定植。ASB孕妇中B族定植率显著高于无ASB孕妇（χ²=17.666，P<0.001）。Logistic回归显示，ASB与妊娠晚期B族阴道定植呈正相关（β=2.577，95%CI=1.509-4.402，P=0.001）。结论 ASB与妊娠晚期B族阴道定植呈正相关。孕早期对ASB进行筛查、预防和控制对减少妊娠晚期B族阴道定植具有重要意义。
