Physics Department, Faculty of Science, Yazd University, 89195-741, Yazd, Iran.
Radiochemistry Division, Bhabha Atomic Research Centre, Mumbai, 400085, India.
Appl Radiat Isot. 2022 Oct;188:110347. doi: 10.1016/j.apradiso.2022.110347. Epub 2022 Jun 30.
In the present study, the theoretical estimation of a combined production of Ga and P radioisotopes were investigated using a medical cyclotron. Protons are used in the Zn(p,n) reaction to produce the medical isotope Ga. The neutrons from the Zn(p,n)Ga reaction are used to launch the S(n,p) reaction to produce P radioisotope. The cross section of these reactions were calculated using TALYS 1.9 code and compared with the available experimental results. SRIM-2013 code was used to calculate the stopping power and range of protons in the Zn target and GEANT4 toolkit was used to evaluate the proton and neutron flux within the Zn and S targets, respectively. The theoretical and simulation production yield of Ga and simulation production yield of P radioisotopes in each reaction were calculated. The results show that the Monte Carlo method can be used for the design and optimization the targets and calculation of production yield for Ga and P radioisotopes.
在本研究中，使用医用回旋加速器研究了 Ga 和 P 放射性同位素的联合生产的理论估算。质子用于 Zn(p,n)反应以产生医用同位素 Ga。来自 Zn(p,n)Ga 反应的中子用于引发 S(n,p)反应以产生 P 放射性同位素。使用 TALYS 1.9 代码计算了这些反应的横截面，并将其与可用的实验结果进行了比较。使用 SRIM-2013 代码计算了 Zn 靶中质子的阻止本领和射程，使用 GEANT4 工具包分别评估了 Zn 和 S 靶中的质子和中子通量。计算了每个反应中 Ga 的理论和模拟产额以及 P 放射性同位素的模拟产额。结果表明，蒙特卡罗方法可用于设计和优化目标以及计算 Ga 和 P 放射性同位素的产额。
