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营养保健品与偏头痛:特定病症治疗的进一步策略。

Nutraceuticals and migraine: further strategy for the treatment of specific conditions.

机构信息

Headache Center, Neurology Unit, University Hospital of Parma, Via Gramsci 14, 43126, Parma, PR, Italy.

Headache Centre, Neurology Unit, AUSL IRCCS Reggio Emilia, 0521 704100, Reggio Emilia, Italy.

出版信息

Neurol Sci. 2022 Nov;43(11):6565-6567. doi: 10.1007/s10072-022-06250-1. Epub 2022 Jul 6.

DOI:10.1007/s10072-022-06250-1
PMID:35792970
Abstract

Nutraceuticals might be defined as food or dietary supplements that provide medicinal or health benefits. Current preventive treatment of migraine includes nutraceuticals as well as conventional drugs. These non-pharmacological therapies, such as magnesium, coenzyme Q10, feverfew, riboflavin, and phycocyanins, are particularly useful in certain categories of patients (adolescents, pregnant or breastfeeding women, the elderly with complex drug therapy, the patient with contraindication to the usual pharmacological therapies) when a conventional drug therapy cannot be prescribed or may be not well tolerated. The evidence currently available confirms a modest efficacy but a very good safety and tolerability profile.

摘要

营养保健品可以被定义为提供药用或保健功效的食物或膳食补充剂。目前,偏头痛的预防治疗包括营养保健品和传统药物。这些非药物治疗方法,如镁、辅酶 Q10、小白菊、核黄素和藻蓝蛋白,在某些特定类别患者(青少年、孕妇或哺乳期妇女、药物治疗复杂的老年人、对常规药物治疗有禁忌症的患者)中特别有用,当常规药物治疗无法开处方或可能不能耐受时。目前可用的证据证实了其适度的疗效,但具有非常好的安全性和耐受性。

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本文引用的文献

1
Comparative study of magnesium, sodium valproate, and concurrent magnesium-sodium valproate therapy in the prevention of migraine headaches: a randomized controlled double-blind trial.镁、丙戊酸钠与镁-丙戊酸钠联合治疗偏头痛的对照研究:一项随机对照双盲试验。
J Headache Pain. 2021 Apr 7;22(1):21. doi: 10.1186/s10194-021-01234-6.
2
Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis.辅酶Q10补充剂用于成人偏头痛患者的预防——一项荟萃分析
BMJ Open. 2021 Jan 5;11(1):e039358. doi: 10.1136/bmjopen-2020-039358.
3
The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations.
营养不良与偏头痛风险的关联:使用客观营养指标评估。
Nutrients. 2023 Sep 1;15(17):3828. doi: 10.3390/nu15173828.
4
Perspectives on Neuronutrition in Prevention and Treatment of Neurological Disorders.神经营养在神经疾病预防和治疗中的观点。
Nutrients. 2023 May 28;15(11):2505. doi: 10.3390/nu15112505.
5
Nutrition and Calcitonin Gene Related Peptide (CGRP) in Migraine.营养与偏头痛中的降钙素基因相关肽 (CGRP)。
Nutrients. 2023 Jan 6;15(2):289. doi: 10.3390/nu15020289.
棕榈酰乙醇胺的药理学及其一些新制剂治疗效果的首批数据。
Br J Pharmacol. 2017 Jun;174(11):1349-1365. doi: 10.1111/bph.13580. Epub 2016 Sep 29.
4
The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview.螺旋藻的抗氧化、免疫调节和抗炎活性:概述。
Arch Toxicol. 2016 Aug;90(8):1817-40. doi: 10.1007/s00204-016-1744-5. Epub 2016 Jun 3.
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A randomized, double-blinded, placebo-controlled, crossover, add-on study of CoEnzyme Q10 in the prevention of pediatric and adolescent migraine.辅酶 Q10 预防儿童和青少年偏头痛的随机、双盲、安慰剂对照、交叉、附加研究。
Cephalalgia. 2011 Jun;31(8):897-905. doi: 10.1177/0333102411406755. Epub 2011 May 17.