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接种 COVID-19 疫苗后伴内耳出血的突发性感觉神经性听力损失。

Sudden sensorineural hearing loss with intralabyrinthine hemorrhage after COVID-19 vaccination.

机构信息

Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

Department of Radiology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

出版信息

Hum Vaccin Immunother. 2022 Nov 30;18(6):2097462. doi: 10.1080/21645515.2022.2097462. Epub 2022 Jul 6.

Abstract

Otologic symptoms of sudden sensorineural hearing loss (SSNHL) have been reported after Coronavirus disease 2019 (COVID-19) vaccinations. However, the association between SSNHL and COVID-19 vaccination has not been clearly established. SSNHL with vertigo can be induced by intralabyrinthine hemorrhage (ILH). The case of a 61-year-old female who was diagnosed SSNHL with ILH after COVID-19 vaccination is presented here. She visited the emergency department for left sudden hearing loss and vertigo that had occurred the previous day. She had received a third booster COVID-19 mRNA vaccination one day prior to the visit; symptoms occurred 6 hours after vaccination. On pure tone audiometry, her hearing threshold indicated deafness in the left ear. A lesion assumed to be ILH was observed on temporal magnetic resonance imaging. She received an oral steroid followed by salvage treatment with intratympanic steroid injection. Three months after symptom onset, her hearing threshold remained deaf with slight improvement at low frequencies in the left ear. Because the symptoms of and prognosis for SSNHL may be worse and vertigo may occur in patients with SSNHL and ILH, careful treatment is required.

摘要

突发性聋(SSNHL)患者在接种 2019 年冠状病毒病(COVID-19)疫苗后出现耳科症状。然而,SSNHL 与 COVID-19 疫苗接种之间的关联尚未明确。内淋巴出血(ILH)可导致伴眩晕的 SSNHL。本文报告了 1 例 61 岁女性患者,在 COVID-19 疫苗接种后因 ILH 并发 SSNHL。她因左耳突发性耳聋和眩晕于前一天就诊于急诊科。她在就诊前一天接受了第三剂 COVID-19 mRNA 疫苗接种;症状在接种后 6 小时出现。纯音测听显示她的左耳听力阈值为聋。颞骨磁共振成像显示病变疑似为 ILH。她接受了口服类固醇治疗,随后进行了鼓室内类固醇注射挽救治疗。在症状出现 3 个月后,她的左耳听力阈值仍为聋,低频有轻微改善。由于 SSNHL 伴 ILH 患者的症状和预后可能更差,且可能出现眩晕,因此需要谨慎治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3686/9746398/5d1d4d6d081e/KHVI_A_2097462_F0001_OC.jpg

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