Stroma New Tune: Emerging Role of PKA in Maintaining Gastric Homeostasis.
作者信息
Cho Charles J, Mills Jason C
机构信息
Department of Medicine, Baylor College of Medicine, Houston, Texas.
Department of Medicine, Department of Pathology and Immunology, and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
出版信息
Cell Mol Gastroenterol Hepatol. 2022;14(3):722-723. doi: 10.1016/j.jcmgh.2022.06.004. Epub 2022 Jul 3.
Abstract
摘要
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Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis.mTORC1 依赖性返老还童促进分化细胞的再生增殖。
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The niche component periostin is produced by cancer-associated fibroblasts, supporting growth of gastric cancer through ERK activation.成纤维细胞分泌的壁蛋白是 niche 成分之一，通过激活 ERK 促进胃癌生长。
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STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.STAT3 在 KRAS 诱导的胰腺肿瘤发生中起着关键作用。
Cancer Res. 2011 Jul 15;71(14):5020-9. doi: 10.1158/0008-5472.CAN-11-0908. Epub 2011 May 17.
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Bone morphogenetic protein signaling regulates gastric epithelial cell development and proliferation in mice.骨形态发生蛋白信号调节小鼠胃上皮细胞的发育和增殖。
Gastroenterology. 2010 Dec;139(6):2050-2060.e2. doi: 10.1053/j.gastro.2010.08.052. Epub 2010 Oct 16.
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