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生酮饮食流行趋势:对体重和血脂管理的影响。

Keto is Trending: Implications for Body Weight and Lipid Management.

机构信息

Midwest Biomedical Research, Suite 3, Addison, IL, USA.

Kasiska Division of Health Sciences, Idaho State University, Pocatello, ID, 83209, USA.

出版信息

Curr Cardiol Rep. 2022 Sep;24(9):1093-1100. doi: 10.1007/s11886-022-01731-3. Epub 2022 Jul 6.

Abstract

PURPOSE OF REVIEW

Very-low-carbohydrate (VLC) and ketogenic diets (KDs) have been used for weight loss and more recently in patients with insulin resistance and type 2 diabetes. The impact of VLC and KDs on lipids/lipoproteins is a concern. The purpose of this review is to discuss the impact of KDs on body weight and lipids/lipoproteins.

RECENT FINDINGS

VLC/KDs contribute to greater weight loss in the short term (< 6 months) compared to higher carbohydrate diets, but there is typically no difference between the diets by 12 months. Triglyceride and high-density lipoprotein cholesterol levels generally improve, but there is a variable response in low-density lipoprotein cholesterol levels, with some individuals experiencing a dramatic increase, particularly those with latent genetic dyslipidemias. Healthcare professionals should educate patients on the risks and benefits of following VLC/KDs and encourage the consumption of carbohydrate-rich foods associated with positive health outcomes.

摘要

目的综述

极低碳水化合物(VLC)和生酮饮食(KDs)已被用于减肥,最近也用于治疗胰岛素抵抗和 2 型糖尿病患者。VLC 和 KDs 对血脂/脂蛋白的影响令人关注。本综述的目的是讨论 KDs 对体重和血脂/脂蛋白的影响。

最近的发现

与高碳水化合物饮食相比,VLC/KD 在短期内(<6 个月)有助于更大程度地减轻体重,但 12 个月后两种饮食之间通常没有差异。甘油三酯和高密度脂蛋白胆固醇水平通常会改善,但低密度脂蛋白胆固醇水平的反应不同,一些人会出现明显升高,特别是那些有潜在遗传性血脂异常的人。医疗保健专业人员应教育患者遵循 VLC/KD 的风险和益处,并鼓励他们食用与健康结果呈正相关的富含碳水化合物的食物。

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