Joe R. and Teresa Lozano Long School of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, USA.
Department of Anesthesiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, USA.
Curr Pain Headache Rep. 2022 Sep;26(9):693-699. doi: 10.1007/s11916-022-01071-5. Epub 2022 Jul 6.
Neuropathic pain is a prevalent and burdensome condition. While oral medical therapies are the first-line treatment for refractory neuropathic pain, in some cases, infusion therapy may be employed. This article is a systematic review of recent publications regarding epidemiologic, pathophysiologic, diagnostic, and therapeutic advancements in the treatment of neuropathic pain using intravenous infusion therapy. Special consideration will be given to relevant and practically used agents and available information on outcomes.
Individuals with neuropathic pain from various etiologies (e.g. trigeminal neuralgia, post-herpetic neuralgia, diabetic neuropathy) often find short-term relief from infusion therapies. However, it is difficult to generalize the findings of these studies to form a standard treatment regimen. The purpose of this paper is to provide clinicians an up-to-date summary of recent literature regarding several infusion therapies in treating neuropathic pain.
神经病理性疼痛是一种普遍且负担沉重的疾病。虽然口服药物治疗是难治性神经病理性疼痛的一线治疗方法,但在某些情况下,可能会采用输注治疗。本文对最近关于静脉输注治疗神经病理性疼痛的流行病学、病理生理学、诊断和治疗进展的出版物进行了系统综述。特别关注相关且实用的药物以及有关结果的可用信息。
患有各种病因(如三叉神经痛、带状疱疹后神经痛、糖尿病性神经病)的神经病理性疼痛患者通常会从输注治疗中获得短期缓解。然而,很难将这些研究的结果推广为标准治疗方案。本文的目的是为临床医生提供有关几种输注治疗神经病理性疼痛的最新文献综述。