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中东和北非地区紧张型头痛负担,1990-2019 年。

Burden of tension-type headache in the Middle East and North Africa region, 1990-2019.

机构信息

Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.

Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Headache Pain. 2022 Jul 6;23(1):77. doi: 10.1186/s10194-022-01445-5.

Abstract

INTRODUCTION

Tension-type headache (TTH) is the most prevalent neurological disorder. As there is a gap in the literature regarding the disease burden attributable to TTH in the Middle East and North Africa (MENA) region, the aim of the present study was to report the epidemiological indicators of TTH in MENA, from 1990 to 2019, by sex, age and socio-demographic index (SDI).

METHODS

Publicly available data on the point prevalence, annual incidence and years lived with disability (YLDs) were retrieved from the global burden of disease (GBD) 2019 study for the 21 countries and territories in MENA, between 1990 and 2019. The results were presented with numbers and age-standardised rates per 100000 population, along with their corresponding 95% uncertainty intervals (UIs).

RESULTS

In 2019, the age-standardised point prevalence and annual incidence rates for TTH in the MENA region were 24504.5 and 8680.1 per 100000, respectively, which represents a 2.0% and a 0.9% increase over 1990-2019, respectively. The age-standardised YLD rate of TTH in this region in 2019 was estimated to be 68.1 per 100000 population, which has increased 1.0% since 1990. Iran [29640.4] had the highest age-standardised point prevalence rate for TTH, while Turkey [21726.3] had the lowest. In 2019, the regional point prevalence of TTH was highest in the 35-39 and 70-74 age groups, for males and females, respectively. Furthermore, the number of prevalent cases was estimated to be highest in those aged 35-39 and 25-29 years, in both males and females, respectively. Moreover, the burden of TTH was not observed to have a clear association with SDI.

CONCLUSIONS

While the prevalence of TTH in the MENA region increased from 1990 to 2019, the incidence rate did not change. In addition, the burden of TTH in MENA was higher than at the global level for both sexes and all age groups. Therefore, prevention of TTH would help alleviate the attributable burden imposed on the hundreds of millions of people suffering from TTH around the region.

摘要

简介

紧张型头痛(TTH)是最常见的神经疾病。由于中东和北非(MENA)地区缺乏有关 TTH 疾病负担的文献,本研究旨在报告 1990 年至 2019 年 MENA 地区 TTH 的流行病学指标,按性别、年龄和社会人口指数(SDI)进行划分。

方法

从全球疾病负担(GBD)2019 年研究中检索了 1990 年至 2019 年 MENA 地区 21 个国家和地区的点患病率、年发病率和伤残调整寿命年(YLDs)的公开可用数据。结果以每 100000 人口的数字和年龄标准化率以及相应的 95%置信区间(UI)表示。

结果

2019 年,MENA 地区 TTH 的年龄标准化点患病率和年发病率分别为 24504.5 和 8680.1/100000,分别比 1990-2019 年增长了 2.0%和 0.9%。2019 年,该地区 TTH 的年龄标准化 YLD 率估计为 68.1/100000 人口,自 1990 年以来增长了 1.0%。伊朗[29640.4]的 TTH 年龄标准化点患病率最高,而土耳其[21726.3]的患病率最低。2019 年,MENA 地区 TTH 的区域点患病率在男性和女性中分别为 35-39 岁和 70-74 岁年龄段最高。此外,男性和女性中,25-29 岁和 35-39 岁年龄组的患者人数估计最多。此外,TTH 的负担与 SDI 没有明显的关联。

结论

虽然 1990 年至 2019 年 MENA 地区 TTH 的患病率有所增加,但发病率并未改变。此外,MENA 地区 TTH 的负担高于全球水平,无论男女和所有年龄组。因此,预防 TTH 将有助于减轻该地区数百万人因 TTH 而遭受的可归因负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be38/9258079/2c86b621fd5f/10194_2022_1445_Fig1_HTML.jpg

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