Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.
Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK.
Aliment Pharmacol Ther. 2022 Sep;56(5):844-856. doi: 10.1111/apt.17132. Epub 2022 Jul 6.
Few studies have demonstrated the impact of irritable bowel syndrome (IBS) on work and activities of daily living.
We collected demographic, gastrointestinal symptom, psychological health and quality of life data from 752 adults with Rome IV-defined IBS. We used the work productivity and activity impairment questionnaire for irritable bowel syndrome and the work and social adjustment scale to examine the degree of both impairment at work and in activities of daily living, as well as factors associated with these.
Of 467 individuals who were employed, 133 (28.5%) reported absenteeism, 373 (85.6%) presenteeism and 382 (81.8%) overall work impairment. A mean of 1.97 hours of work per week was lost due to IBS. Extrapolating this across the entire UK, we estimate that between 72 and 188 million hours of work are lost per year due to IBS in individuals of working age. Among all 752 participants, 684 (91.0%) reported any activity impairment with 220 (29.3%) reporting impairment in home management, 423 (56.3%) in social leisure activities, 207 (27.5%) in private leisure activities, and 203 (27.0%) in maintaining close relationships. Severe IBS, higher levels of anxiety, depression, somatization and gastrointestinal symptom-specific anxiety, and lower levels of IBS-related quality of life were associated with impairment in both work and activities of daily living.
Patients with IBS experience a substantial impact on their work and activities of daily living because of their IBS. Future studies should assess the impact of medical interventions on the ability to work and participate in social activities.
很少有研究表明肠易激综合征（IBS）对工作和日常生活活动的影响。
我们从 752 名符合罗马 IV 标准的 IBS 成人中收集了人口统计学、胃肠道症状、心理健康和生活质量数据。我们使用肠易激综合征工作生产力和活动障碍问卷以及工作和社会调整量表来检查工作和日常生活活动中障碍的程度，以及与这些相关的因素。
在 467 名就业的个体中，133 名（28.5%）报告缺勤，373 名（85.6%）存在在职现象，382 名（81.8%）整体工作障碍。每周因 IBS 损失平均 1.97 小时的工作时间。根据这个数据在整个英国进行推断，我们估计每年因工作年龄个体的 IBS 导致 7200 万至 1.88 亿小时的工作时间损失。在所有 752 名参与者中，684 名（91.0%）报告存在任何活动障碍，其中 220 名（29.3%）报告在家庭管理方面存在障碍，423 名（56.3%）在社会休闲活动方面存在障碍，207 名（27.5%）在私人休闲活动方面存在障碍，203 名（27.0%）在维持亲密关系方面存在障碍。严重的 IBS、更高的焦虑、抑郁、躯体化和胃肠道症状特异性焦虑水平，以及更低的 IBS 相关生活质量与工作和日常生活活动障碍有关。
IBS 患者因 IBS 而对工作和日常生活活动产生了重大影响。未来的研究应该评估医疗干预对工作能力和参与社会活动能力的影响。
