From the Epidemiology and Population Health Program, BC Centre for Excellence in HIV/AIDS.
Sex Transm Dis. 2022 Oct 1;49(10):706-712. doi: 10.1097/OLQ.0000000000001672. Epub 2022 Jul 7.
Gay, bisexual, and other men who have sex with men (gbMSM) remain disproportionately affected by human immunodeficiency virus (HIV). Interaction between psychosocial factors likely plays a role in HIV acquisition risk. We aimed to analyze the association of loneliness and self-rated attractiveness with HIV acquisition risk, and determine whether these associations were mediated by gay telephone chatlines or online dating platforms.
This cross-sectional study included HIV-negative gbMSM 16 years or older enrolled into the Momentum Health Study from February 2012 to February 2015. Loneliness, self-rated attractiveness (exposures) and use of gay chatlines or online dating platforms (mediators) were assessed through self-interviews. Human immunodeficiency virus acquisition risk (outcome) was assessed by the HIV Incidence Risk Index. Weighted logistic regression modeled the association and moderation effect between exposures and outcome. Mediation models estimated 3-way direct effect among exposures, mediators, and outcome.
Of 542 gbMSM, those who were lonely (adjusted odds ratio [aOR], 1.54; 95% confidence intervals [CI], 1.04-2.28) and attractive (aOR, 1.69; 95% CI, 1.04-2.76) had increased odds for HIV acquisition risk. Our moderation analysis demonstrated a heightened joint effect among lonely and attractive participants (aOR, 1.70; 95% CI, 1.08-2.65). Use of gay telephone chatlines or online dating platforms mediated 30.5% of the association between loneliness and HIV acquisition risk, but did not mediate attractiveness and HIV acquisition risk.
Our findings suggest that the provision of interventions focusing on mental health support and safer sex practices through gay telephone chatlines or online dating platforms is promising to help alleviate the HIV burden among gbMSM.
男同性恋者、双性恋者和其他与男性发生性关系的男性(gbMSM)仍然不成比例地受到人类免疫缺陷病毒(HIV)的影响。心理社会因素之间的相互作用可能在 HIV 获得风险中起作用。我们旨在分析孤独感和自我吸引力与 HIV 获得风险的关联,并确定这些关联是否通过男同性恋电话聊天或在线约会平台来介导。
这项横断面研究包括 2012 年 2 月至 2015 年 2 月期间参加“动力健康研究”的 16 岁及以上的 HIV 阴性 gbMSM。通过自我访谈评估孤独感、自我吸引力(暴露)和使用男同性恋电话聊天或在线约会平台(中介)。通过 HIV 发病率风险指数评估 HIV 获得风险(结局)。加权逻辑回归模型评估了暴露与结局之间的关联和调节作用。中介模型估计了暴露、中介和结局之间的 3 路直接效应。
在 542 名 gbMSM 中,孤独(调整后的优势比 [aOR],1.54;95%置信区间 [CI],1.04-2.28)和有吸引力(aOR,1.69;95% CI,1.04-2.76)的参与者发生 HIV 获得风险的几率增加。我们的调节分析表明,孤独和有吸引力的参与者之间存在增强的联合效应(aOR,1.70;95% CI,1.08-2.65)。男同性恋电话聊天或在线约会平台的使用部分解释了孤独感与 HIV 获得风险之间的关联(30.5%),但没有解释吸引力与 HIV 获得风险之间的关联。
我们的研究结果表明,通过男同性恋电话聊天或在线约会平台提供专注于心理健康支持和安全性行为的干预措施,有望帮助减轻 gbMSM 的 HIV 负担。