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苏丹东部加达里夫医院内科病房成年住院患者/入院情况及死亡率的模式与趋势:一项四年回顾性研究

Pattern and Trends in Adult Hospitalization/Admission and Mortality Among Medical Ward Inpatients at Gadarif Hospital in Eastern Sudan: A Four-Year Retrospective Study.

作者信息

Omar Saeed M, Osman Osama S, Gasim Gasim I, Adam Ishag

机构信息

Faculty of Medicine, Gadarif University, Gadarif, Sudan.

Klerksdorp/Tshepong Hospital Complex, the University of Witwatersrand, Johannesburg, South Africa.

出版信息

Int J Gen Med. 2022 Jun 30;15:5879-5889. doi: 10.2147/IJGM.S367513. eCollection 2022.

Abstract

PURPOSE

Sub-Saharan Africa suffers from a dual impact of communicable (CDs) and non-communicable diseases (NCDs). There is scarce data on causes, trends of admission, and deaths among patients in Sudan. We aimed to determine the causes, trends of admission, and mortality among adult patients admitted to Gadarif Hospital in Eastern Sudan.

PATIENTS AND METHODS

The medical records of adult patients admitted to Gadarif medical wards from January 2017 to December 2020 were reviewed for age, gender, causes of admission, and outcomes. Multivariate Cox regression analysis was used to analysis factors (age, sex, years, and disease) associated with the mortality.

RESULTS

Of the 7230 patients who were admitted, 2221 (34.7%) were females and 5009 (69.3%) were males. The median age (interquartile range, IQR) was 47.0 (35.0) years. Of these 7230 patients, 3167 (43.8%) and 4063 (56.2%) patients were admitted with CDs and NCDs, respectively. Cardiovascular diseases (18.4%), snakebites (12.9%), and visceral leishmaniasis (12.0%) were the most common causes of admission. The overall in-patient adult deaths were 674 (9.3%). Cardiovascular diseases (22.3%), neurological diseases (16.9%), sepsis (15.9%), renal diseases (13.9%), and snakebites (8.3%) were the most common causes of inpatient mortality. Malignancy (20.7%), sepsis (20.9%), neurological diseases (17.4%), and cardiovascular diseases (13.8%) comprised the highest case fatality rates among the admitted patients. Using a Cox regression model (adjusted), age (adjusted hazard ratio = 1.02, 95% confidence interval = 1.01‒1.03) was associated with increased mortality hazard. However, the gender and years of admission were not associated with increased mortality hazard.

CONCLUSION

Admissions and mortality rates for CDs and NCDs are high compared with other African countries. Preventive measures are required to avert the high burden of these diseases. Health care systems in Sudan need to be prepared to deal with the dual burden of the diseases.

摘要

目的

撒哈拉以南非洲地区遭受传染病(CDs)和非传染病(NCDs)的双重影响。苏丹患者病因、入院趋势及死亡情况的数据匮乏。我们旨在确定苏丹东部加达里夫医院成年住院患者的病因、入院趋势及死亡率。

患者与方法

回顾2017年1月至2020年12月期间加达里夫内科病房成年患者的病历,记录年龄、性别、入院原因及转归。采用多因素Cox回归分析来分析与死亡率相关的因素(年龄、性别、年份和疾病)。

结果

7230例入院患者中,女性2221例(34.7%),男性5009例(69.3%)。年龄中位数(四分位间距,IQR)为47.0(35.0)岁。这7230例患者中,分别有3167例(43.8%)和4063例(56.2%)因传染病和非传染病入院。心血管疾病(18.4%)、蛇咬伤(12.9%)和内脏利什曼病(12.0%)是最常见的入院原因。成年住院患者总死亡674例(9.3%)。心血管疾病(22.3%)、神经系统疾病(16.9%)、败血症(15.9%)、肾脏疾病(13.9%)和蛇咬伤(8.3%)是住院死亡的最常见原因。恶性肿瘤(20.7%)、败血症(20.9%)、神经系统疾病(17.4%)和心血管疾病(13.8%)在入院患者中病死率最高。使用Cox回归模型(校正后),年龄(校正风险比 = 1.02,95%置信区间 = 1.01‒1.03)与死亡风险增加相关。然而,性别和入院年份与死亡风险增加无关。

结论

与其他非洲国家相比,传染病和非传染病的入院率和死亡率较高。需要采取预防措施以避免这些疾病的高负担。苏丹的医疗保健系统需要做好应对这些疾病双重负担的准备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bccd/9252602/0b43aaba861c/IJGM-15-5879-g0001.jpg

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